Eksborg S, Edsmyr F, Andersson I
Eur Urol. 1985;11(5):309-11. doi: 10.1159/000472525.
The bladder capacities of 75 patients with superficial bladder tumors were measured prior to and during monthly intravesical instillation therapy with adriamycin. When taken off therapy, a decrease in bladder capacity of more than 20% was observed in 18 of the patients. In 14 of the treated patients an increase in bladder capacity of more than 20% was observed. In patients with reduced bladder capacity when taken off therapy, there were no correlations between the degree of decreased bladder capacity and the number of instillations or the total instilled amount of adriamycin, indicating that the observed decrease in bladder capacity was caused by the underlying disease and not by the treatment per se.
对75例浅表性膀胱肿瘤患者在每月进行阿霉素膀胱灌注治疗之前及治疗期间测量膀胱容量。在停止治疗时，18例患者观察到膀胱容量减少超过20%。在14例接受治疗的患者中观察到膀胱容量增加超过20%。在停止治疗时膀胱容量降低的患者中，膀胱容量降低程度与灌注次数或阿霉素总灌注量之间无相关性，这表明观察到的膀胱容量降低是由基础疾病引起的，而非治疗本身所致。
