Panichi G, Pantosti A, Gentile G, Testore G P, Venditti M, Martino P, Serra P
Eur J Cancer Clin Oncol. 1985 Oct;21(10):1159-63. doi: 10.1016/0277-5379(85)90008-2.
Leukemia patients with diarrhea or other abdominal symptoms have been investigated for the presence of Clostridium difficile and its cytotoxin in stools. Of the patients studied 19% had C. difficile, in most cases together with cytotoxin. All patients but one had received antibiotics, while one had been treated with cytotoxic agents only. Symptoms of colitis were most often abdominal pain and distension rather than diarrhea. Owing to the not infrequent fatal evolution, it is recommended that routine search for C. difficile in leukemia patients with abdominal symptoms be performed and appropriate therapy started immediately.
对患有腹泻或其他腹部症状的白血病患者进行了粪便中艰难梭菌及其细胞毒素的检测。在研究的患者中，19%检测出艰难梭菌，大多数情况下同时伴有细胞毒素。除一名患者外，所有患者都接受过抗生素治疗，而另一名患者仅接受过细胞毒性药物治疗。结肠炎的症状最常见的是腹痛和腹胀，而非腹泻。由于病情往往会致命性进展，建议对有腹部症状的白血病患者常规检测艰难梭菌，并立即开始适当治疗。
