Pedí Vaneide Daciane, Porto Denise Lopes, de Jesus Martins Wagner, de França Giovanny Vinícius Araújo
Emerg Infect Dis. 2025 Sep;31(9):1718-1728. doi: 10.3201/eid3109.250554. Epub 2025 Aug 5.
We describe 7,421 chikungunya hospitalizations in Brazil covered by the country's unified health system during 2014-2024. Most (43.2%) hospitalizations occurred in 2016 and 2017, reaching 0.72 (95% CI 0.69-0.76) hospitalizations/100,000 population in 2016. Hospitalizations were more frequent among persons who were female (55.8%), identifying as brown or black (63.5%), and 1-19 years of age (31.4%). Intensive care unit admissions occurred in 1.4% of cases, predominantly among children <5 and adults >85 years of age. The overall in-hospital case-fatality rate was 1.1%, which increased substantially with age, reaching 11.5% among patients >90 years of age and 14.1% among men 85-89 years of age. Patients admitted to the intensive care unit had a case-fatality rate of 21.1%. The total cost of chikungunya hospitalizations was US $560,746 (US $76.26 per patient). Our findings provide insights for surveillance of the most severe chikungunya cases.
我们描述了2014年至2024年期间巴西统一卫生系统覆盖的7421例基孔肯雅热住院病例。大多数（43.2%）住院病例发生在2016年和2017年，2016年的住院率达到0.72（95%置信区间0.69 - 0.76）例/10万人口。女性（55.8%）、认定为棕色或黑色人种（63.5%）以及1 - 19岁（31.4%）的人群住院更为频繁。1.4%的病例入住了重症监护病房，主要是5岁以下儿童和85岁以上成年人。总体住院病死率为1.1%，随年龄大幅增加，90岁以上患者中达到11.5%，85 - 89岁男性中达到14.1%。入住重症监护病房的患者病死率为21.1%。基孔肯雅热住院病例的总费用为560,746美元（每位患者76.26美元）。我们的研究结果为最严重基孔肯雅热病例的监测提供了见解。
