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腹腔镜腹膜阴道成形术与乙状结肠阴道成形术治疗先天性无阴道的对比研究

Comparative study of laparoscopic peritoneal vaginoplasty versus sigmoid colon vaginoplasty in the treatment of congenital absence of vagina.

作者信息

Yinuo Li, Zihan Li, Xiaorui Lin, Yuting Li, Yibao Huang, Rong Liu, Mingfu Wu

机构信息

National Clinical Research Center for Obstetrical and Gynecological Diseases, Department of Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Avenue, Wuhan, Hubei Province, 430030, China.

Key Laboratory of Cancer Invasion and Metastasis, Ministry of Education, Wuhan, 430030, China.

出版信息

Surg Endosc. 2025 Aug 5. doi: 10.1007/s00464-025-11868-1.

Abstract

OBJECTIVE

This study aimed to compare laparoscopic peritoneal vaginoplasty and laparoscopic sigmoid colon vaginoplasty in patients with congenital absence of vagina, aiming to provide more robust guidance for clinicians and patients with congenital absence of vagina in choosing the most appropriate surgical approach.

METHODS

Patients with congenital absence of vagina who underwent laparoscopic vaginoplasty in our hospital from 2011 to 2023 were included in this study. Participants were divided into two groups: the laparoscopic peritoneal vaginoplasty group (peritoneal group, n = 20) and the laparoscopic sigmoid colon vaginoplasty group (sigmoid colon group, n = 30). Short-term outcomes (operative duration, intraoperative hemorrhage, postoperative ventilation time, time to resume oral intake, length of postoperative hospital stay,) and long-term outcomes (sexual satisfaction, vaginal discharge odor, complications, vaginal mold duration) were evaluated.

RESULTS

Comparative analysis revealed that the peritoneal group demonstrated significantly reduced operative duration (p < 0.01), accelerated postoperative ventilation recovery (p < 0.01), and earlier resumption of oral intake (p < 0.01). No significant intergroup differences were observed in intraoperative blood loss (p = 0.10), length of postoperative hospital stay (p = 0.52), or vaginal discharge odor (p = 1). The peritoneal group had shorter vaginal mold use (p < 0.05) and higher sexual satisfaction (p < 0.01). While the peritoneal group showed a trend toward lower postoperative complication rates (3% vs. 8%), this difference did not reach statistical significance (p = 0.53).

CONCLUSIONS

Laparoscopic peritoneal vaginoplasty demonstrates superior perioperative outcomes, optimized intestinal function restoration, reduced requirement for vaginal mold application, and improved sexual satisfaction in patients with congenital absence of vagina. This procedure shows promise as a preferred surgical approach in clinical practice.

摘要

目的

本研究旨在比较腹腔镜腹膜阴道成形术和腹腔镜乙状结肠阴道成形术治疗先天性无阴道患者的效果,为临床医生和先天性无阴道患者选择最合适的手术方式提供更有力的指导。

方法

纳入2011年至2023年在我院接受腹腔镜阴道成形术的先天性无阴道患者。参与者分为两组:腹腔镜腹膜阴道成形术组(腹膜组,n = 20)和腹腔镜乙状结肠阴道成形术组(乙状结肠组,n = 30)。评估短期结局(手术时长、术中出血量、术后通气时间、恢复经口进食时间、术后住院时间)和长期结局(性满意度、阴道分泌物异味、并发症、阴道模具使用时长)。

结果

对比分析显示,腹膜组手术时长显著缩短(p < 0.01),术后通气恢复加快(p < 0.01),经口进食恢复更早(p < 0.01)。术中出血量(p = 0.10)、术后住院时间(p = 0.52)或阴道分泌物异味(p = 1)在组间未观察到显著差异。腹膜组阴道模具使用时间较短(p < 0.05),性满意度较高(p < 0.01)。虽然腹膜组术后并发症发生率有降低趋势(3% 对 8%),但差异未达到统计学意义(p = 0.53)。

结论

腹腔镜腹膜阴道成形术在先天性无阴道患者中显示出更好的围手术期结局、优化的肠道功能恢复、减少的阴道模具使用需求以及更高的性满意度。该手术有望成为临床实践中首选的手术方式。

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