Xu Xiaolong, Lv Meng, Wang Cheng, Mei Jianfeng
Department of Hepatobiliary-Pancreatic-Spleen-Gastrointestinal Surgery Surgeon, Lanxi People's Hospital, Jinhua, 321100, Zhejiang Province, China.
Department of Ophthalmology, Lanxi People's Hospital, Jinhua, Zhejiang Province, China.
Eur J Med Res. 2025 Aug 5;30(1):707. doi: 10.1186/s40001-025-02968-8.
The spleen is also the largest lymphoid organ and has important immune and haematopoietic functions. Traumatic splenic rupture often results in haemorrhagic shock and is life-threatening. In the past, total splenectomy was performed for various degrees of splenic injury, which caused great harm to the patient. Over the past few decades, the treatment of blunt splenic injury has also changed significantly, from total splenectomy to a focus on procedures that preserve splenic function. At the same time, the use of splenic artery embolization in high-grade splenic injuries has also reduced the failure rate of non-surgical treatment and the incidence of conversion to open splenectomy.
According to the American Association for the Surgery of Trauma (AAST) spleen injury grading, this study selected 80 patients treated in our emergency department for blunt splenic injuries of grade II-III between 1 January 2023 and 1 January 2025. These patients were the study subjects (40 patients received partial splenic artery embolization (intervention group) and 40 patients received splenectomy (control group)). The clinical therapeutic outcomes of the two treatment approaches were analysed by SPSS.
In contrast to the control group, patients in the intervention group exhibited reduced operation time, time to first flatus, time to removal of drainage tubes and hospitalization time. Furthermore, the incidence of surgical complications was found to be lower in the intervention group than in the control group. The T lymphocyte CD4 + /CD8 values of the intervention group were higher than those in the control group at 2 and 4 weeks postoperatively, and the difference was statistically significant (P < 0.05).
Partial splenic artery embolization has obvious advantages in the treatment of grade II-III blunt splenic injuries, and provides data support and reference significance for the selection of treatment methods for low-grade blunt splenic injuries.
This study is a statistical analysis of relevant data for patients who have received a medical intervention and therefore does not involve trial registration.
脾脏也是最大的淋巴器官，具有重要的免疫和造血功能。外伤性脾破裂常导致失血性休克，危及生命。过去，对于不同程度的脾损伤均行全脾切除术，给患者造成了极大伤害。在过去几十年中，钝性脾损伤的治疗也发生了显著变化，从全脾切除术转变为注重保留脾功能的手术。同时，脾动脉栓塞术在高级别脾损伤中的应用也降低了非手术治疗的失败率和转为开腹脾切除术的发生率。
根据美国创伤外科学会（AAST）的脾损伤分级，本研究选取了2023年1月1日至2025年1月1日期间在我院急诊科接受治疗的80例II-III级钝性脾损伤患者。这些患者为研究对象（40例患者接受部分脾动脉栓塞术（干预组），40例患者接受脾切除术（对照组））。采用SPSS分析两种治疗方法的临床治疗效果。
与对照组相比，干预组患者的手术时间、首次排气时间、引流管拔除时间和住院时间均缩短。此外，发现干预组的手术并发症发生率低于对照组。干预组术后2周和4周的T淋巴细胞CD4 + /CD8值高于对照组，差异有统计学意义（P < 0.05）。
部分脾动脉栓塞术在治疗II-III级钝性脾损伤方面具有明显优势，为低级别钝性脾损伤治疗方法的选择提供了数据支持和参考意义。
本研究是对接受医学干预患者的相关数据进行统计分析，因此不涉及试验注册。
