Caviglia Marta, Ucciero Andrealuna, Conti Andrea, Di Filippo Aurora, Trotta Francesco, Ragazzoni Luca, Della Corte Francesco, Barone-Adesi Francesco
Centre for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università del Piemonte Orientale, Novara, Italy.
Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.
Anaesthesia. 2025 Aug 6. doi: 10.1111/anae.16709.
Inhalational anaesthetics contribute to greenhouse gas emissions, leading to regulatory restrictions in some countries. This study analysed time trends of greenhouse gas emissions directly attributable to the use of volatile anaesthetic agents in 41 countries.
Sales data were obtained using data from IQVIA MIDAS® and national medicines agencies. We calculated the kilograms of carbon dioxide equivalents (based on global warming potential) per capita and percentage change in greenhouse gas emissions, from the emission of volatile anaesthetics from 2018 to 2023.
Data were obtained for 41 countries, representing approximately 35% of the global population. Greenhouse gas emissions associated with volatile anaesthetic agents decreased in the 27 European Union nations and other 'western' countries included in the study (Australia, Canada, New Zealand, UK and USA), achieving in some cases below 0.5 kg of carbon dioxide equivalents per inhabitant. In contrast, several Asian countries showed a substantial increase in emissions, with South Korea and Japan reporting the highest values globally (approximately 2.5 kg of carbon dioxide equivalents per inhabitant). A secondary analysis restricted to European countries showed a 17-fold difference in per-capita carbon-equivalent emissions between the highest and lowest emitters, suggesting that recommendations on the use of volatile anaesthetic agents are implemented inconsistently.
Our study highlighted large differences in the management of greenhouse gas emissions attributable to volatile anaesthetic use. While results show a decreasing trend in western countries, albeit with substantial variation, rising trends observed in many Asian countries may constitute a source of concern. The experience of nations that have phased out the highest impacting volatile anaesthetic agents show that reducing emissions below 0.5 kg of carbon dioxide equivalents per inhabitant is attainable. This should serve as a model for other systems, prompting implementation of educational initiatives and specific policies.
吸入性麻醉剂会导致温室气体排放,这在一些国家引发了监管限制。本研究分析了41个国家中挥发性麻醉剂使用所直接导致的温室气体排放的时间趋势。
使用IQVIA MIDAS®和各国药品机构的数据获取销售数据。我们计算了2018年至2023年挥发性麻醉剂排放的人均二氧化碳当量(基于全球变暖潜能值)千克数以及温室气体排放的百分比变化。
获取了41个国家的数据,约占全球人口的35%。研究中包括的27个欧盟国家和其他“西方”国家(澳大利亚、加拿大、新西兰、英国和美国)与挥发性麻醉剂相关的温室气体排放有所减少,在某些情况下人均低于0.5千克二氧化碳当量。相比之下,几个亚洲国家的排放量大幅增加,韩国和日本的排放量在全球最高(约人均2.5千克二氧化碳当量)。一项仅限于欧洲国家的二次分析显示,排放最高和最低的国家之间人均碳当量排放量相差17倍,这表明关于挥发性麻醉剂使用的建议执行情况不一致。
我们的研究突出了挥发性麻醉剂使用所导致的温室气体排放管理方面的巨大差异。虽然结果显示西方国家呈下降趋势,尽管存在很大差异,但许多亚洲国家观察到的上升趋势可能令人担忧。已逐步淘汰影响最大的挥发性麻醉剂的国家的经验表明,将人均排放量降至0.5千克二氧化碳当量以下是可以实现的。这应为其他体系树立榜样,促使开展教育举措并实施具体政策。