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一名18岁女性急性哮喘加重期出现脊髓积气:1例罕见病例报告

Pneumorrhachis in Acute Asthma Exacerbation in an 18-Year-Old Female Patient: A Report of a Rare Case.

作者信息

Abdelaziz Omar, Abid Hashim, Yusuf Ado, Uppal Nickh

机构信息

Internal Medicine, Manchester University National Health Service (NHS) Foundation Trust, Manchester, GBR.

Radiology, Manchester University National Health Service (NHS) Foundation Trust, Manchester, GBR.

出版信息

Cureus. 2025 Jul 5;17(7):e87331. doi: 10.7759/cureus.87331. eCollection 2025 Jul.

DOI:10.7759/cureus.87331
PMID:40765593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12322184/
Abstract

Pneumorrhachis (intraspinal air) is a rare radiological finding, often associated with trauma, iatrogenic causes, or increased intrathoracic pressures. We present a case of pneumorrhachis secondary to severe asthma exacerbation, highlighting its pathophysiology and clinical implications. An 18-year-old female patient presented with a history of dry cough, chest tightness, and pain in her neck. Subsequent scans, including chest X-rays and computed tomography (CT) scans, showed a large volume pneumomediastinum and pneumorrhachis. The patient was managed conservatively with bronchodilators, corticosteroids, and supplemental oxygen, leading to the resolution of symptoms and radiographic abnormalities.  This case illustrates that pneumorrhachis can occur in asthma due to increased intrathoracic pressure, leading to air dissection into the spinal canal. Conservative management suffices in most cases, as seen here.  Pneumorrhachis should be considered in severe asthma exacerbations with pneumomediastinum, even in the absence of neurological symptoms. Early recognition and treatment of the underlying asthma are crucial to prevent complications. This case adds to the limited literature on pneumorrhachis in non-traumatic settings.

摘要

脊髓积气(椎管内积气)是一种罕见的影像学表现,常与外伤、医源性因素或胸内压力升高有关。我们报告一例继发于严重哮喘加重的脊髓积气病例,强调其病理生理学和临床意义。一名18岁女性患者,有干咳、胸闷和颈部疼痛病史。随后的检查,包括胸部X光和计算机断层扫描(CT),显示大量纵隔积气和脊髓积气。该患者接受了支气管扩张剂、皮质类固醇和补充氧气的保守治疗,症状和影像学异常得以缓解。 本病例表明,由于胸内压力升高,哮喘患者可发生脊髓积气,导致气体进入椎管。如本例所示,大多数情况下保守治疗就足够了。即使没有神经症状,在伴有纵隔积气的严重哮喘加重病例中也应考虑脊髓积气。早期识别和治疗潜在的哮喘对于预防并发症至关重要。本病例补充了非创伤性情况下关于脊髓积气的有限文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/d8799286b30b/cureus-0017-00000087331-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/b2d4907c4971/cureus-0017-00000087331-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/9fa48f74c62e/cureus-0017-00000087331-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/32718e88f19f/cureus-0017-00000087331-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/d8799286b30b/cureus-0017-00000087331-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/b2d4907c4971/cureus-0017-00000087331-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/9fa48f74c62e/cureus-0017-00000087331-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/32718e88f19f/cureus-0017-00000087331-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0df/12322184/d8799286b30b/cureus-0017-00000087331-i04.jpg

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本文引用的文献

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A rare case of spontaneous giant pneumorrachis presenting with cauda equina syndrome: a case report.自发性巨大硬脊膜气肿致马尾综合征 1 例报告
Spinal Cord Ser Cases. 2024 Apr 8;10(1):18. doi: 10.1038/s41394-024-00631-8.
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Narrative review of traumatic pneumorrhachis.创伤性脊髓积气的叙述性综述。
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Pneumorrhachis secondary to exacerbation of asthma: A case report and literature review.哮喘加重继发脊髓积气:一例报告及文献综述
Respirol Case Rep. 2023 Oct 9;11(11):e01228. doi: 10.1002/rcr2.1228. eCollection 2023 Nov.
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Spontaneous Pneumorachis - A Case-Based Review.自发性脊髓积气——基于病例的综述
J Asthma Allergy. 2021 Dec 18;14:1539-1554. doi: 10.2147/JAA.S325293. eCollection 2021.
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Pneumorrhachis, pneumomediastinum, pneumopericardium and subcutaneous emphysema as complications of bronchial asthma.气胸、纵隔气肿、心包积气和皮下气肿是支气管哮喘的并发症。
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