超越基础：通过针对免疫功能低下患者的巨细胞病毒免疫球蛋白来重新思考抗菌药物管理。
Beyond the basics: rethinking antimicrobial stewardship by targeting cytomegalovirus immune globulin for immunocompromised patients.
作者信息
Prasad Ritika, Lu Brian, Veloria Daniella, Mui Emily, Nelson Joanna, Dhillon Gundeep, Deresinski Stanley, Holubar Marisa, Alegria William
机构信息
Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Department of Quality, Safety & Health Equity, Stanford University School of Medicine, Stanford, CA, USA.
出版信息
Antimicrob Steward Healthc Epidemiol. 2025 Jul 31;5(1):e166. doi: 10.1017/ash.2025.10074. eCollection 2025.
Identifying actionable stewardship targets in immunocompromised patients is challenging due to limited data and high morbidity. One approach could be targeting therapy with limited evidence, like cytomegalovirus immune globulin (CMV-IGIV). We implemented a drug restriction program that increased appropriate use of CMV-IGIV, highlighting a unique stewardship opportunity in immunocompromised populations.
由于数据有限且发病率高，在免疫功能低下患者中确定可采取行动的管理目标具有挑战性。一种方法可能是针对证据有限的治疗方法，如巨细胞病毒免疫球蛋白（CMV-IGIV）。我们实施了一项药物限制计划，该计划增加了CMV-IGIV的合理使用，突出了免疫功能低下人群中独特的管理机会。
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