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胆石症背景下的特发性嗜酸性粒细胞性胆囊炎：一例报告及文献综述

Idiopathic Eosinophilic Cholecystitis in the Setting of Cholelithiasis: A Case Report and Brief Literature Review.

作者信息

Sigdel Smara, Wilson Stephen, Habib Elaria, Diks John

机构信息

Pathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.

Surgery, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.

出版信息

Cureus. 2025 Aug 5;17(8):e89424. doi: 10.7759/cureus.89424. eCollection 2025 Aug.

DOI:10.7759/cureus.89424
PMID:40766096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12323892/
Abstract

Eosinophilic cholecystitis (EC) is a rare inflammatory condition characterized by prominent eosinophilic infiltration of the gallbladder wall. It often mimics typical acute cholecystitis and is usually diagnosed only after histopathological examination. This case report discusses a 69-year-old woman presenting with symptoms of acute cholecystitis who was later found to have EC. The report highlights the clinical presentation, diagnosis, treatment, and relevant literature on this uncommon condition.

摘要

嗜酸性粒细胞性胆囊炎（EC）是一种罕见的炎症性疾病，其特征为胆囊壁有明显的嗜酸性粒细胞浸润。它常酷似典型的急性胆囊炎，通常仅在组织病理学检查后才能确诊。本病例报告讨论了一名69岁出现急性胆囊炎症状的女性，后来被发现患有嗜酸性粒细胞性胆囊炎。该报告重点介绍了这种罕见病症的临床表现、诊断、治疗及相关文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8a6/12323892/76f13cd7bee5/cureus-0017-00000089424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8a6/12323892/4c467442be90/cureus-0017-00000089424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8a6/12323892/76f13cd7bee5/cureus-0017-00000089424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8a6/12323892/4c467442be90/cureus-0017-00000089424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8a6/12323892/76f13cd7bee5/cureus-0017-00000089424-i02.jpg

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本文引用的文献

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Severe Idiopathic Hypereosinophilic Syndrome with Eosinophilic Cholecystitis in a Child Treated with Mepolizumab.用美泊利珠单抗治疗的儿童严重特发性高嗜酸性粒细胞综合征伴嗜酸性胆囊炎
Indian J Pediatr. 2024 May;91(5):526. doi: 10.1007/s12098-023-05007-8. Epub 2023 Dec 30.
2
Eosinophilic Cholecystitis and Eosinophils in Gallbladder Injuries: A Clinicopathological Analysis of 1050 Cholecystectomies.嗜酸性粒细胞性胆囊炎与胆囊损伤中的嗜酸性粒细胞：1050例胆囊切除术的临床病理分析
Diagnostics (Basel). 2023 Aug 1;13(15):2559. doi: 10.3390/diagnostics13152559.
3
Sustained Eosinophilic Cholangitis Due to a Mite Allergy Mimicking Sclerosing Cholangitis.
由尘螨过敏引起的持续性嗜酸性胆管炎，类似于硬化性胆管炎。
Intern Med. 2022 Aug 15;61(16):2477-2482. doi: 10.2169/internalmedicine.8323-21. Epub 2022 Feb 1.
4
An unusual case of a gallbladder polyp.胆囊息肉样病变 1 例
Acta Gastroenterol Belg. 2021 Oct-Dec;84(4):675-677. doi: 10.51821/84.4.013.
5
Eosinophilic Cholangitis with Poor Prognosis after Corticosteroid- and Ursodeoxycholic Acid-Related Remission of Peripheral and Peribiliary Eosinophilia.在皮质类固醇和熊去氧胆酸使外周及胆管周围嗜酸性粒细胞增多症缓解后预后不良的嗜酸性胆管炎
Case Rep Gastroenterol. 2021 Feb 18;15(1):232-243. doi: 10.1159/000512420. eCollection 2021 Jan-Apr.
6
Pathophysiology and pathology of acute cholecystitis: A secondary publication of the Japanese version from 1992.急性胆囊炎的病理生理学与病理学：1992年日文版的二次出版
J Hepatobiliary Pancreat Sci. 2022 Feb;29(2):212-216. doi: 10.1002/jhbp.912. Epub 2021 Mar 27.
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Eosinophilic Cholecystitis Associated with Eosinophilic Granulomatosis with Polyangiitis.嗜酸性胆囊炎合并嗜酸性肉芽肿性多血管炎
Case Rep Gastroenterol. 2020 Dec 11;14(3):668-674. doi: 10.1159/000511863. eCollection 2020 Sep-Dec.
8
Hypereosinophilic Syndrome, Multiorgan Involvement and Response to Imatinib.高嗜酸性粒细胞综合征、多器官受累及对伊马替尼的反应
Cureus. 2020 Jun 7;12(6):e8493. doi: 10.7759/cureus.8493.
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