成人急性呼吸窘迫综合征患者的体外生命支持
Extracorporeal life support for adult patients with ARDS.
作者信息
Combes Alain, Supady Alexander, Abrams Darryl, Agerstrand Cara, Badulak Jenelle, Camporota Luigi, Fan Eddy, Ferguson Niall D, Fraser John F, Hodgson Carol, Jaber Samir, MacLaren Graeme, Patel Brijesh V, Peek Giles J, Schmidt Matthieu, Shekar Kiran, Slutsky Arthur S, Brodie Daniel
机构信息
Institute of Cardiometabolism and Nutrition, Sorbonne Université INSERM Unité Mixte de Recherche (UMRS) 1166, Paris, France.
Service de Médecine Intensive-Réanimation, Institut de Cardiologie, Assistance Publique-Hôpitaux de Paris (APHP) Hôpital Pitié-Salpêtrière, Paris, France.
出版信息
Intensive Care Med. 2025 Aug 6. doi: 10.1007/s00134-025-08070-1.
Extracorporeal Life Support (ECLS), including venovenous (VV) extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) is a temporary support option for patients with severe respiratory failure. Current data and recent guidelines support the use of VV ECMO for select patients with very severe respiratory failure as this technique might improve survival in appropriately selected patients. Patient selection criteria, timing of ECMO initiation and optimal management of mechanical ventilation and anticoagulation, and other adjunctive treatment options are a matter of ongoing research.
体外生命支持（ECLS），包括静脉-静脉（VV）体外膜肺氧合（ECMO）和体外二氧化碳清除（ECCO2R），是重症呼吸衰竭患者的一种临时支持选择。目前的数据和近期指南支持对部分极重度呼吸衰竭患者使用VV ECMO，因为该技术可能会提高适当选择患者的生存率。患者选择标准、启动ECMO的时机、机械通气和抗凝的优化管理以及其他辅助治疗选择仍是正在研究的课题。
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