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80岁以上腹主动脉瘤患者死亡相关因素分析

Analysis of Mortality-Related Factors in Patients Aged >80 Years Treated for Abdominal Aortic Aneurysms.

作者信息

Kim Juan, Chung Sung Woon, Kim Jongwon, Bae Miju, Lee Chung Won, Huh Up

机构信息

Department of Thoracic and Cardiovascular Surgery, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine, Yangsan, Korea.

出版信息

J Chest Surg. 2025 Sep 5;58(5):196-204. doi: 10.5090/jcs.25.003. Epub 2025 Aug 7.

DOI:10.5090/jcs.25.003
PMID:40769764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12415430/
Abstract

BACKGROUND

With an aging population, the number of patients over 80 undergoing abdominal aortic aneurysm (AAA) repair is increasing. This study examines factors associated with mortality in these patients.

METHODS

A retrospective cohort study involving 66 patients aged >80 who underwent AAA repair between January 2010 and December 2022 was conducted. Baseline characteristics, treatment methods (open surgical repair [OSR] or endovascular aneurysm repair [EVAR]), post-treatment mortality, complications, and reinterventions were analyzed.

RESULTS

The mean age of patients was 82.74±2.64 years, with men comprising 74.2%. The OSR group had significantly younger patients than the EVAR group (81.92 years vs. 83.28 years, p=0.04). Rupture prevalence was significantly higher in the OSR group (27% vs. 7.5%, p=0.03). No significant difference was found in 30-day mortality rates between the OSR and EVAR groups (11.5% vs. 10%, p=0.85). Univariate logistic regression identified emergency surgery (odds ratio [OR], 6.18; p=0.04), post-treatment pneumonia (OR, 7.47; 95% confidence interval [CI], 1.00-55.70; p=0.05), and vasopressor use (OR, 44.57; p<0.01) as significant factors associated with 30-day mortality. Cox proportional hazard regression revealed age (hazard ratio [HR], 1.19; p=0.02), preoperative bedridden state (HR, 22.24; p<0.01), sacrifice of both internal iliac arteries (HR, 5.26; p=0.04), and postoperative vasopressor use (HR, 30.04; p<0.01) as significant predictors of overall mortality.

CONCLUSION

In patients aged >80 years, aneurysm rupture and emergency operation significantly increased 30-day mortality following AAA repair. Preoperative bedridden status, management of internal iliac arteries, and postoperative vasopressor use were significant predictors of overall mortality. When determining surgical indications and predicting outcomes, careful attention should be given to factors influencing mortality throughout the entire surgical process.

摘要

背景

随着人口老龄化,80岁以上接受腹主动脉瘤(AAA)修复术的患者数量不断增加。本研究探讨了这些患者死亡的相关因素。

方法

进行了一项回顾性队列研究,纳入了2010年1月至2022年12月期间66例年龄>80岁且接受AAA修复术的患者。分析了基线特征、治疗方法(开放手术修复[OSR]或血管腔内动脉瘤修复[EVAR])、治疗后死亡率、并发症和再次干预情况。

结果

患者的平均年龄为82.74±2.64岁,男性占74.2%。OSR组患者的年龄显著低于EVAR组(81.92岁对83.28岁,p=0.04)。OSR组的破裂发生率显著更高(27%对7.5%,p=0.03)。OSR组和EVAR组的30天死亡率无显著差异(11.5%对10%,p=0.85)。单因素逻辑回归确定急诊手术(比值比[OR],6.18;p=

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f298/12415430/2ea836628dd6/jcs-58-5-196-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f298/12415430/64e55e629b40/jcs-58-5-196-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f298/12415430/2ea836628dd6/jcs-58-5-196-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f298/12415430/64e55e629b40/jcs-58-5-196-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f298/12415430/2ea836628dd6/jcs-58-5-196-f2.jpg

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本文引用的文献

1
Failure to preserve the internal iliac artery during abdominal aortic aneurysm repair is associated with mortality and ischemic complications.在腹主动脉瘤修复过程中,如果未能保留髂内动脉,会导致死亡率和缺血性并发症增加。
J Vasc Surg. 2022 Jul;76(1):122-131. doi: 10.1016/j.jvs.2021.11.077. Epub 2021 Dec 23.
2
The Association Between Preoperative Independent Ambulatory Status and Outcomes After Open Abdominal Aortic Aneurysm Repairs.开放性腹主动脉瘤修复术后术前独立行走状态与预后的关联
Ann Vasc Surg. 2022 Apr;81:70-78. doi: 10.1016/j.avsg.2021.10.050. Epub 2021 Nov 14.
3
Systematic review and meta-analysis of the prevalence of abdominal aortic aneurysm in Asian populations.
系统评价和荟萃分析亚洲人群腹主动脉瘤的患病率。
J Vasc Surg. 2021 Mar;73(3):1069-1074.e1. doi: 10.1016/j.jvs.2020.08.140. Epub 2020 Sep 26.
4
Systematic Review and Meta-Analysis of Outcomes of Open and Endovascular Repair of Ruptured Abdominal Aortic Aneurysm in Patients with Hostile vs. Friendly Aortic Anatomy.开放手术与血管内修复治疗伴敌对性与友善性主动脉解剖患者破裂腹主动脉瘤的系统评价和荟萃分析。
Eur J Vasc Endovasc Surg. 2020 May;59(5):717-728. doi: 10.1016/j.ejvs.2019.12.024. Epub 2020 Jan 14.
5
Outcome of Ruptured Abdominal Aortic Aneurysm Repair in Octogenarians: A Systematic Review and Meta-Analysis.高龄患者腹主动脉瘤破裂修复的结局:系统评价和荟萃分析。
Eur J Vasc Endovasc Surg. 2020 Jan;59(1):16-22. doi: 10.1016/j.ejvs.2019.07.014. Epub 2019 Dec 4.
6
Systematic review and meta-analysis of sex differences in outcomes after endovascular aneurysm repair for infrarenal abdominal aortic aneurysm.系统评价和荟萃分析:血管内动脉瘤修复治疗肾下腹部主动脉瘤后结局的性别差异。
J Vasc Surg. 2020 Jan;71(1):283-296.e4. doi: 10.1016/j.jvs.2019.06.105. Epub 2019 Aug 26.
7
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J Vasc Surg. 2019 Dec;70(6):1823-1830. doi: 10.1016/j.jvs.2019.01.081. Epub 2019 May 21.
8
Advancing front of old-age human survival.老年人生存前沿的推进。
Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11209-11214. doi: 10.1073/pnas.1812337115. Epub 2018 Oct 16.
9
Editor's Choice - Assessment of International Outcomes of Intact Abdominal Aortic Aneurysm Repair over 9 Years.编辑推荐——9年期间完整腹主动脉瘤修复的国际结局评估
Eur J Vasc Endovasc Surg. 2017 Jul;54(1):13-20. doi: 10.1016/j.ejvs.2017.03.003. Epub 2017 Apr 13.
10
Endovascular versus open repair of abdominal aortic aneurysm in 15-years' follow-up of the UK endovascular aneurysm repair trial 1 (EVAR trial 1): a randomised controlled trial.英国血管内动脉瘤修复试验 1(EVAR 试验 1)15 年随访的血管内与开放修复腹主动脉瘤的比较:一项随机对照试验。
Lancet. 2016 Nov 12;388(10058):2366-2374. doi: 10.1016/S0140-6736(16)31135-7. Epub 2016 Oct 12.