Cen Ran, Chen Li-Xia, Liu Chun, Nie Rong-Bin, Tao Zhu, Xiao Xin
Guizhou Key Laboratory of Macrocyclic and Supramolecular Chemistry, School of Chemistry and Chemical Engineering, Guizhou University, Guiyang, 550025, China.
School of Culture and Tourism, Guiyang Healthcare Vocational University, Guiyang, 550081, China.
Mikrochim Acta. 2025 Aug 6;192(9):564. doi: 10.1007/s00604-025-07438-w.
A sensing strategy to significantly enhance the aggregation-induced emission (AIE) of berberine hydrochloride (BBR) is proposed. A supramolecular framework material was prepared by using 5-sulfosalicylic acid (SSA) and nor-seco-cucurbit[10]uril (ns-Q[10]). Single crystal structure analysis confirmed that the SSA@ns-Q[10] assembly forms a ternary complex. SSA@ns-Q[10] assembly can induce BBR aggregation to a large extent, which leads to the enhancement of fluorescence intensity of mixed solution. The results showed that SSA@ns-Q[10] assembly can be used as an excellent fluorescent sensing material for detecting BBR. This assembly has been successfully applied to the detection of BBR in human serum samples, highlighting its potential for use in both environmental and biological systems. Additionally, the SSA@ns-Q[10]‒BBR system shows promise for a variety of applications, including anti-counterfeiting, screen printing, and the production of fluorescent-emitting handicrafts.
提出了一种显著增强盐酸小檗碱（BBR）聚集诱导发光（AIE）的传感策略。使用5-磺基水杨酸（SSA）和去甲-次-葫芦脲[10]（ns-Q[10]）制备了一种超分子框架材料。单晶结构分析证实SSA@ns-Q[10]组装体形成了三元复合物。SSA@ns-Q[10]组装体能够在很大程度上诱导BBR聚集，这导致混合溶液荧光强度增强。结果表明，SSA@ns-Q[10]组装体可作为检测BBR的优异荧光传感材料。该组装体已成功应用于人血清样品中BBR的检测，突出了其在环境和生物系统中的应用潜力。此外，SSA@ns-Q[10]‒BBR体系在包括防伪、丝网印刷和荧光发光手工艺品生产等多种应用中显示出前景。
