Bouayad Abdellatif, El Oumri Ahmed Amine
Laboratory of Immunology, Faculty of Medicine and Pharmacy Oujda, Mohammed First University, Oujda-Angad 4867, Oriental, Morocco.
Physical Medicine and Rehabilitation, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda-Angad 4867, Oriental, Morocco.
World J Clin Cases. 2025 Aug 6;13(22):105331. doi: 10.12998/wjcc.v13.i22.105331.
This letter to the editor highlights adding the diagnostic utility of immunoglobulin G4 (IgG4) measurements and its potential role in IgG4-related spinal pachymeningitis (IgG4-RSP) pathogenesis to the case reported by Chae TS , which focused on IgG4-RSP diagnosis based on magnetic resonance imaging findings and increased plasma IgG4 concentrations. A comprehensive understanding of both IgG4 serological and cerebrospinal fluid biomarkers is essential for managing this complex condition.
这封给编辑的信强调了在Chae TS报道的病例中增加免疫球蛋白G4（IgG4）测量的诊断效用及其在IgG4相关脊髓硬脊膜炎（IgG4-RSP）发病机制中的潜在作用，该病例主要基于磁共振成像结果和血浆IgG4浓度升高来诊断IgG4-RSP。全面了解IgG4血清学和脑脊液生物标志物对于管理这种复杂疾病至关重要。
