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全主动脉弓置换术后急性胰腺炎导致包裹性坏死:一例病例报告及文献复习

Acute pancreatitis after total aortic arch replacement leading to walled-off necrosis: A case report and review of literature.

作者信息

Inoue Yuma, Yata Yutaka, Yokota Yuta, Li Zhao-Liang, Kawabata Kazumi

机构信息

Department of Gastroenterology, Hanwa Memorial Hospital, Osaka 558-0041, Japan.

Department of Hepatology, Osaka Metropolitan University, Osaka 545-0051, Japan.

出版信息

World J Clin Cases. 2025 Aug 6;13(22):104165. doi: 10.12998/wjcc.v13.i22.104165.

Abstract

BACKGROUND

Although acute pancreatitis and walled-off necrosis (WON) are rare complications following aortic surgery, they are serious risk factors for postoperative mortality. Considering the poor general condition of the postoperative patient, more effective and less invasive treatments are favorable.

CASE SUMMARY

A 67-year-old man was referred to our hospital for the treatment of WON after acute pancreatitis. He had undergone total aortic arch replacement due to aortic arch aneurysm and coronary artery bypass grafting due to angina pectoris 6 weeks prior in another hospital. On the second postoperative day, laboratory data and computed tomography showed that the patient had developed acute pancreatitis. Although conservative management (antibiotics, hydration, ) had helped in relieving the symptoms of acute pancreatitis, peripancreatic fluid collection (PFC) persisted, accompanied by duodenal obstruction and vomiting. Contrast-enhanced computed tomography showed that the heterogeneous enhancement and fluid collection in the pancreatic body and tail had increased, consistent with walled-off WON. We therefore performed endoscopic ultrasound-guided transluminal drainage for the PFC. As a result, the WON resolved gradually, resulting in improved oral intake.

CONCLUSION

Acute pancreatitis is a rare gastrointestinal complication following thoracic and thoracoabdominal aortic aneurysm surgery. To the best of our knowledge, this is the first case of WON after aortic arch surgery treated with endoscopic ultrasound-guided transluminal drainage for PFC.

摘要

背景

尽管急性胰腺炎和包裹性坏死(WON)是主动脉手术后罕见的并发症,但它们是术后死亡的严重危险因素。考虑到术后患者的一般状况较差,更有效且侵入性较小的治疗方法是可取的。

病例摘要

一名67岁男性因急性胰腺炎后WON被转诊至我院治疗。他6周前在另一家医院因主动脉弓瘤接受了全主动脉弓置换术,并因心绞痛接受了冠状动脉旁路移植术。术后第二天,实验室检查数据和计算机断层扫描显示患者发生了急性胰腺炎。尽管保守治疗(抗生素、补液等)有助于缓解急性胰腺炎的症状,但胰周积液(PFC)持续存在,并伴有十二指肠梗阻和呕吐。增强计算机断层扫描显示胰体和胰尾的不均匀强化和积液增加,符合包裹性WON。因此,我们对PFC进行了内镜超声引导下的腔内引流。结果,WON逐渐消退,患者的经口摄入量得以改善。

结论

急性胰腺炎是胸主动脉和胸腹主动脉瘤手术后罕见的胃肠道并发症。据我们所知,这是首例采用内镜超声引导下的腔内引流治疗主动脉弓手术后WON伴PFC的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16a1/12188756/18420c9cf0cc/wjcc-13-22-104165-g001.jpg

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