Kamo Hikaru, Oyama Genko, Nagaki Koichi, Hattori Nobutaka
Department of Neurology, Juntendo University School of Medicine, Bunkyo, Japan.
Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Front Neurol. 2025 Jul 23;16:1609823. doi: 10.3389/fneur.2025.1609823. eCollection 2025.
To date, disease-modifying therapies have not been established for Parkinson's disease (PD) or atypical parkinsonisms. Exercise has been reported to help maintain functional abilities and delay disease progression. However, no consensus exists regarding the type, amount, or timing of exercise for each disease stage. Therefore, this study aimed to quantify rehabilitation interventions and identify optimal approaches based on patient characteristics.
Participants diagnosed with PD or related disorders and residing in an elderly care facility received various rehabilitation therapies-including water stimulation bed, therapeutic massage, sit-to-stand training, gait training, cycle ergometer training, aerobic training using treadmill, stretching, balance training, calisthenics, and resistance training-while wearing a wearable device between April and May 2022. The following parameters were evaluated: differences in body surface temperature and pulse rate before and after rehabilitation, calories burned, steps taken during rehabilitation, and upper and lower extremity activity indices.
A total of 49 participants were included, and the frequency of rehabilitation sessions was determined at the discretion of the therapist based on each participant's condition. Each rehabilitation session was quantified and visualized using radar charts.
This study offers insight into the quantification and visualization of rehabilitation effects in patients with progressive neurodegenerative diseases presenting with parkinsonism. Future efforts should focus on accumulating data under standardized conditions and assessing motor symptoms longitudinally to develop personalized rehabilitation programs for patients with neurodegenerative disorders.
迄今为止，尚未确立针对帕金森病（PD）或非典型帕金森综合征的疾病修饰疗法。据报道，运动有助于维持功能能力并延缓疾病进展。然而，对于每个疾病阶段的运动类型、运动量或运动时间，尚无共识。因此，本研究旨在量化康复干预措施，并根据患者特征确定最佳方法。
2022年4月至5月期间，居住在老年护理机构且被诊断为PD或相关疾病的参与者在佩戴可穿戴设备的同时接受了各种康复治疗，包括水刺激床、治疗性按摩、坐立训练、步态训练、自行车测力计训练、使用跑步机的有氧训练、伸展运动、平衡训练、健身操和阻力训练。评估了以下参数：康复前后体表温度和脉搏率的差异、燃烧的卡路里、康复期间的步数以及上下肢活动指数。
共纳入49名参与者，康复治疗的频率由治疗师根据每位参与者的情况自行决定。每次康复治疗都使用雷达图进行量化和可视化。
本研究为帕金森综合征相关进行性神经退行性疾病患者康复效果的量化和可视化提供了见解。未来的工作应集中在标准化条件下积累数据，并纵向评估运动症状，以便为神经退行性疾病患者制定个性化的康复计划。
