Lee Jiyeon, Cho Seong Ah, Choi Seoyoon, Han Eunbi, Shin Hyeri, Park Yoo Kyoung
Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea.
Korea Medical Foods Co., Ltd., Seoul 04779, Korea.
Clin Nutr Res. 2025 Jul 29;14(3):191-203. doi: 10.7762/cnr.2025.14.3.191. eCollection 2025 Jul.
This study evaluated the effects of replacing skipped meals with oral nutritional supplements (ONS) on the nutritional status and functional health of older adults. A total of 29 participants aged ≥ 65 years who regularly skipped at least one meal per day were included in this single-arm study. For 8 weeks, participants consumed two packs of ONS daily (150 mL each, providing 400 kcal and 18 g of protein) as a substitute for skipped meals. Nutritional status, nutrient intake, body composition, and physical function were assessed before and after the intervention. The Nutrition Quotient for the Elderly score significantly increased from 58.97 to 63.62 (p = 0.014). Total nutrient intake, including ONS, significantly improved compared with baseline (p < 0.01). Body weight and body mass index increased significantly from 58.87 to 59.47 kg (p = 0.028) and from 23.9 to 24.18 kg/m (p = 0.016), respectively. Calf circumference decreased significantly from 34.1 to 33.39 cm (p = 0.010). Physical function, assessed using the Short Physical Performance Battery, showed significant improvement (p = 0.003). In conclusion, replacing skipped meals with ONS may enhance nutritional status and support functional health in older adults.
Clinical Research Information Service Identifier: KCT0010184.
本研究评估了用口服营养补充剂（ONS）替代不进食餐次对老年人营养状况和功能健康的影响。本单臂研究共纳入了29名年龄≥65岁且每天经常至少不吃一餐的参与者。在8周时间里，参与者每天食用两包ONS（每包150毫升，提供400千卡热量和18克蛋白质）以替代不进食的餐次。在干预前后评估了营养状况、营养素摄入量、身体成分和身体功能。老年人营养商数得分从58.97显著提高到63.62（p = 0.014）。包括ONS在内的总营养素摄入量与基线相比显著改善（p < 0.01）。体重和体重指数分别从58.87显著增加到59.47千克（p = 0.028）和从23.9增加到24.18千克/米²（p = 0.016）。小腿围从34.1显著减小到33.39厘米（p = 0.010）。使用简短身体性能测试电池评估的身体功能显示出显著改善（p = 0.003）。总之，用ONS替代不进食餐次可能会改善老年人的营养状况并支持其功能健康。
临床研究信息服务标识符：KCT0010184。
