The clearance of gentamicin from antibiotic-loaded bone cement.
作者信息
Downes S, Brown A E, Mukherjee S
出版信息
Int Orthop. 1985;9(3):205-7. doi: 10.1007/BF00268172.
PMID:4077341
Abstract
The concentrations of Gentamicin in the serum, drainage fluid and urine were determined by radioimmunoassay in 40 patients after total hip replacement and 10 after knee replacement. Palacos R bone cement with added Gentamicin had been used to fix the prostheses in all cases. Two types of response were observed; in Group I the Gentamicin levels rose very rapidly, whereas in Group II a more gradual increase was seen. In all cases the level of Gentamicin had fallen to a negligible amount by the fifth day after operation.
摘要
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