Kalsotra Sidhant, Froass Dillon, Gupta Aneesha, Amaya Sebastian, Tobias Joseph D, Olbrecht Vanessa A
Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, United States.
College of Medicine, The Ohio State University, Columbus, OH, United States.
J Med Internet Res. 2025 Aug 7;27:e68348. doi: 10.2196/68348.
Ineffective postoperative pain management affects more than 25% of hospitalized children, leading to increased morbidity, impaired physical function, delayed recovery, prolonged opioid use, and heightened health care costs. Traditional pharmacological interventions have limitations, particularly given growing concerns over long-term opioid use in pediatric populations. Virtual reality (VR) has emerged as a promising nonpharmacological intervention for pediatric pain management, offering immersive, multisensory experiences that can effectively distract and engage patients' attention away from pain sensations. This viewpoint examines the current evidence and prospects for VR as a component of pediatric multimodal pain management strategies. Several VR modalities have shown potential for reducing pain and anxiety in pediatric populations, including virtual reality-distraction therapy, virtual reality-exposure therapy, virtual reality-guided relaxation-based therapy, and virtual reality-biofeedback therapy. The neurobiological underpinnings of VR's analgesic effects involve multiple mechanisms: the gate control theory explains how intense multisensory VR inputs compete with pain signal transmission, while the attention-modulation pathways involving the anterior cingulate cortex and periaqueductal gray work alongside emotional regulation pathways through amygdala connections to reduce pain perception. Recent studies involving various pediatric surgical populations have demonstrated VR's potential to reduce postoperative pain intensity, pain unpleasantness, anxiety, and in some cases, the need for rescue analgesia. However, VR's analgesic effects appear to be transient, typically lasting 15-30 minutes, which suggests the need for optimization in timing and frequency of VR sessions. Implementation challenges include cost considerations, technological access disparities, logistical requirements for safe use and storage, and staff training needs. As hospitals and health care systems continue to explore nonpharmacological pain management strategies, VR represents a promising adjunct to traditional approaches, potentially reducing reliance on opioid medications while improving patient experience and outcomes. Throughout this viewpoint, we address the major concepts related to VR, the use of VR in differing clinical situations, various VR-based therapy methods, and the practicality of VR to alleviate pain, as well as several key findings to date and future directions.
无效的术后疼痛管理影响超过25%的住院儿童,导致发病率增加、身体功能受损、恢复延迟、阿片类药物使用时间延长以及医疗保健成本增加。传统的药物干预存在局限性,尤其是考虑到对儿科人群长期使用阿片类药物的担忧日益增加。虚拟现实(VR)已成为儿科疼痛管理中一种有前景的非药物干预手段,提供沉浸式、多感官体验,可有效分散患者注意力,使其注意力从疼痛感觉上转移。本文观点探讨了VR作为儿科多模式疼痛管理策略组成部分的现有证据和前景。几种VR模式已显示出在减轻儿科人群疼痛和焦虑方面的潜力,包括虚拟现实分散疗法、虚拟现实暴露疗法、虚拟现实引导的基于放松的疗法以及虚拟现实生物反馈疗法。VR镇痛作用的神经生物学基础涉及多种机制:闸门控制理论解释了强烈的多感官VR输入如何与疼痛信号传递竞争,而涉及前扣带回皮质和导水管周围灰质的注意力调节通路与通过杏仁核连接的情绪调节通路协同作用,以降低疼痛感知。最近涉及各种儿科手术人群的研究表明,VR有潜力降低术后疼痛强度、疼痛不适感、焦虑,在某些情况下,还可减少急救镇痛的需求。然而,VR的镇痛效果似乎是短暂的,通常持续15 - 30分钟,这表明需要优化VR治疗的时间和频率。实施挑战包括成本考量、技术获取差距、安全使用和存储的后勤要求以及工作人员培训需求。随着医院和医疗保健系统继续探索非药物疼痛管理策略,VR是传统方法的一种有前景的辅助手段,有可能减少对阿片类药物的依赖,同时改善患者体验和治疗结果。在本文观点中,我们阐述了与VR相关的主要概念、VR在不同临床情况下的应用、各种基于VR的治疗方法、VR缓解疼痛的实用性,以及迄今为止的一些关键发现和未来方向。