Samami Mohammad, Jafari Elham, Hassanipour Soheil, Naghipour Mohammadreza, Joukar Farahnaz, Mansour-Ghanaei Fariborz
Department of Oral and Maxillofacial Medicine, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Razi Hospital, Sardar-Jangle Ave, P.O. Box: 41448-95655, Rasht, Iran.
Sci Rep. 2025 Aug 7;15(1):28888. doi: 10.1038/s41598-025-13744-3.
Studies investigating the association between gastroesophageal reflux disease (GERD) and the decayed, missing, and filled teeth (DMFT) index have yielded contradictory results. Therefore, this study aimed to determine this relationship in the PERSIAN Guilan Cohort Study (PGCS) population. This analytical cross-sectional study was part of the PGCS. Demographic, clinical, and oral hygiene information were collected. DMFT scores were specified by clinical examination, and GERD status was determined based on self-reported symptoms and confirmation by a medical specialist. Among 10,520 individuals in the PGCS, 13.2% (95% CI 12.5-13.8%) were diagnosed with GERD. The mean DMFT for the GERD group was 14.41 ± 8.47 and 14.59 ± 8.82 for the non-GERD group, and the difference was not statistically significant (P = 0.49). Linear regression analysis showed that older age, lower education and body mass index (BMI), smoking, alcohol consumption, higher wealth score index (WSI), and not tooth brushing were associated with an increased DMFT in the GERD group (P < 0.05). Findings indicate no association between GERD and an increased risk of dental caries in PGCS. These results should be interpreted cautiously, and longitudinal studies are needed to understand this relationship. The results demonstrated that tooth brushing exerts a substantial influence on both groups.
调查胃食管反流病(GERD)与龋失补牙指数(DMFT)之间关联的研究得出了相互矛盾的结果。因此,本研究旨在确定波斯语吉兰队列研究(PGCS)人群中的这种关系。这项分析性横断面研究是PGCS的一部分。收集了人口统计学、临床和口腔卫生信息。通过临床检查确定DMFT评分,并根据自我报告的症状和医学专家的确认来确定GERD状态。在PGCS的10520名个体中,13.2%(95%CI 12.5 - 13.8%)被诊断患有GERD。GERD组的平均DMFT为14.41±8.47,非GERD组为14.59±8.82,差异无统计学意义(P = 0.49)。线性回归分析表明,年龄较大、教育程度较低、体重指数(BMI)较低、吸烟、饮酒、财富得分指数(WSI)较高以及不刷牙与GERD组DMFT升高相关(P < 0.05)。研究结果表明PGCS中GERD与龋齿风险增加之间无关联。这些结果应谨慎解读,需要进行纵向研究以了解这种关系。结果表明刷牙对两组都有重大影响。