Sugihara Eiji, Bhatia Ansh, Shibuya Masahiko, Miyazaki Koichi, Nakata Masaya, Kawabe Atsuhiko, Nakasone Takashi, Okuno Yuji
Department of Radiology, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-Ku, Tokyo, 160-0023, Japan.
Department of Interventional Radiology, Okuno Clinic Tokyo, 4th Fl Ginrei Bldg., 7-8-4, Roppongi, Minato-Ku, Tokyo, 106-0032, Japan.
Cardiovasc Intervent Radiol. 2025 Aug 7. doi: 10.1007/s00270-025-04144-1.
This study aimed to evaluate the short- to mid-term outcomes of transcatheter arterial microembolization (TAME) as a therapeutic intervention for pain and disability associated with chronic Achilles tendonitis (AT) refractory to conservative treatment.
This multicenter retrospective study included 82 patients (67 men and 15 women) who underwent TAMEs using imipenem/cilastatin sodium for refractory chronic AT between May 2019 and February 2023. The mean age was 47.3 ± 12.7 years. A Numerical Rating Scale (NRS, 0-10) was used to assess pain at baseline and 1, 2, 3, 6, 12, and 24 months. Clinical success was defined as a decrease of > 50% in the NRS score at 12 months compared with baseline. The Victorian Institute of Sports Assessment (VISA-A) score was used to evaluate pain and function at baseline and 6 and 24 months.
Clinical success was achieved in 67 (81.7%) of the 82 patients. The baseline mean NRS was 6.7 ± 1.5, which improved to 4.2 ± 2.0, 3.3 ± 2.0, 2.8 ± 2.2, 2.3 ± 2.2, 1.8 ± 2.2, and 1.5 ± 2.2 at 1, 2, 3, 6, 12, and 24 months, respectively (all p < 0.001). The mean baseline VISA-A score was 48.4 ± 19.1, which improved to 76.9 ± 17.4 and 82.2 ± 17.0 at 6 and 24 months, respectively (all p < 0.001). No major complications or tendon ruptures were observed during the 2 year follow-up period.
TAME for chronic AT is a safe and effective treatment that improves long-term functional outcomes and can be offered to patients resistant to conservative management.
本研究旨在评估经导管动脉微栓塞术(TAME)作为一种治疗干预措施,用于治疗对保守治疗无效的慢性跟腱炎(AT)相关疼痛和功能障碍的短期至中期疗效。
这项多中心回顾性研究纳入了82例患者(67例男性和15例女性),他们在2019年5月至2023年2月期间接受了使用亚胺培南/西司他丁钠的TAME治疗难治性慢性AT。平均年龄为47.3±12.7岁。采用数字评分量表(NRS,0 - 10)在基线以及1、2、3、6、12和24个月时评估疼痛情况。临床成功定义为与基线相比,12个月时NRS评分降低>50%。采用维多利亚运动评估协会(VISA - A)评分在基线以及6和24个月时评估疼痛和功能。
82例患者中有67例(81.7%)取得了临床成功。基线时NRS平均评分为6.7±1.5,在1、2、3、6、12和24个月时分别改善至4.2±2.0、3.3±2.0、2.8±2.2、2.3±2.2、1.8±2.2和1.5±2.2(所有p<0.001)。基线时VISA - A平均评分为48.4±19.1,在6和24个月时分别改善至76.9±17.4和82.2±17.0(所有p<0.001)。在2年随访期内未观察到重大并发症或肌腱断裂。
TAME治疗慢性AT是一种安全有效的治疗方法,可改善长期功能结局,可提供给对保守治疗耐药的患者。