Cochran James, Deng Nancy, Tabbaa Ameer, Razi Afshin, Abu-Ghanem Sara
Department of Otolaryngology, State University of New York (SUNY) Downstate Health Sciences University, Brooklyn, NY, USA.
College of Medicine, State University of New York (SUNY) Downstate Health Sciences University, Brooklyn, NY, USA.
Dysphagia. 2025 Aug 8. doi: 10.1007/s00455-025-10867-7.
Anterior cervical discectomy and fusion (ACDF) is a well-established surgical procedure, with wide variation in reported postoperative dysphagia rates (1-79%). No standardized guidelines exist for screening, diagnosis, and treatment of postoperative ACDF dysphagia. The goal of the current study is to utilize a large database of US healthcare insurance claims to investigate incidence of dysphagia post-ACDF as well as risk factors for dysphagia and interventions performed in a large patient cohort. PearlDiver database was used to identify patients without preoperative dysphagia undergoing ACDF between 2010 and 2022 and create cohorts of patients with and without postoperative ACDF dysphagia. International Classification of Disease version 9 and 10 (ICD-9 and ICD-10), and Current Procedural Terminology (CPT) codes were used to retrieve patient records. The two cohorts were compared in terms of age, gender, comorbidities, prior neck surgery, postoperative vocal fold paralysis, and dysphagia related interventions. OR with 95% CI were calculated, stratifying by various risk factors. Prevalence of various postoperative diagnoses and interventions were calculated. Of 618,170 patients undergoing primary ACDF from 2010 to 2022, 88,899 (14.4%) developed postoperative dysphagia. Females, smokers, diabetics, and obese patients had higher odds of developing post ACDF dysphagia (OR 1.14, 2.51, 2.18, 2.50 respectively). 3% of patients with post ACDF dysphagia had new postoperative vocal fold motion impairment (VFMI) versus 0.3% without dysphagia (OR 8.69). Within the dysphagia cohort,14.9% underwent laryngoscopy, 19.0% underwent MBSS, 0.80% underwent FEES, and 5.2% received swallow therapy. Dysphagia is commonly diagnosed after ACDF, with females, smokers, diabetics, and obese patients having the highest odds of diagnosis. Yet, a low percentage of patients are being referred for evaluation or treatment. Providers performing ACDF should consider screening protocols and early referral to providers offering interventions for dysphagia diagnosis and treatment.
颈椎前路椎间盘切除融合术(ACDF)是一种成熟的外科手术,报道的术后吞咽困难发生率差异很大(1%-79%)。目前尚无关于术后ACDF吞咽困难筛查、诊断和治疗的标准化指南。本研究的目的是利用美国医疗保险索赔的大型数据库,调查ACDF术后吞咽困难的发生率、吞咽困难的风险因素以及在大型患者队列中实施的干预措施。使用PearlDiver数据库识别2010年至2022年间接受ACDF且术前无吞咽困难的患者,并创建有和没有ACDF术后吞咽困难的患者队列。使用国际疾病分类第9版和第10版(ICD-9和ICD-10)以及当前手术操作术语(CPT)代码检索患者记录。比较了两个队列在年龄、性别、合并症、既往颈部手术、术后声带麻痹和吞咽困难相关干预方面的情况。计算了95%置信区间的比值比(OR),并按各种风险因素进行分层。计算了各种术后诊断和干预的患病率。在2010年至2022年间接受初次ACDF的618170例患者中,88899例(14.4%)出现了术后吞咽困难。女性、吸烟者、糖尿病患者和肥胖患者发生ACDF术后吞咽困难的几率更高(OR分别为1.14、2.51、2.18、2.50)。ACDF术后吞咽困难患者中有3%出现了新的术后声带运动障碍(VFMI),而无吞咽困难患者中这一比例为0.3%(OR 8.69)。在吞咽困难队列中,14.9%的患者接受了喉镜检查,19.0%的患者接受了吞钡食管造影,0.80%的患者接受了纤维内镜吞咽功能检查,5.2%的患者接受了吞咽治疗。吞咽困难在ACDF术后很常见,女性、吸烟者、糖尿病患者和肥胖患者被诊断出的几率最高。然而,只有一小部分患者被转诊进行评估或治疗。实施ACDF的医疗人员应考虑筛查方案,并尽早转诊至提供吞咽困难诊断和治疗干预措施的医疗人员处。