Tsuda Akai, Oura Daisuke, Ihara Riku
Department of Radiology, Otaru General Hospital, 1-1-1 Wakamatsu, Otaru, Hokkaido, 047-8550, Japan.
Department of Biomedical Science and Engineering, Faculty of Health Sciences, Hokkaido University, Sapporo, Hokkaido, Japan.
Radiol Phys Technol. 2025 Aug 7. doi: 10.1007/s12194-025-00948-5.
In acute ischemic stroke (AIS), where the shortest possible assessment is required to minimize time to mechanical thrombectomy (MT). With recent advancements in MRI reconstruction technology, MRI has also become valuable in the decision-making process for AIS treatment planning. In this study, we compared the examination times of our MRI protocol with those of a standard CT protocol for evaluating AIS through phantom simulations to obtain timing information directly relevant to treatment strategies, and evaluated the utility of MRI for MT. Ten radiological technologists performed scans using the same phantom for each modality. Evaluation items included time for hemorrhage detection, time for penumbra evaluation, and time for brain artery evaluation, and total examination time. The total examination time was slightly shorter with CT (696.2 ± 52.7 s) compared to MRI (701.8 ± 15.8 s), although this difference was not statistically significant (p = 0.4). For other parameters, MRI demonstrated significantly faster detection times: hemorrhage detection (CT, 80.9 ± 12.8 s; MRI, 66.3 ± 1.7 s; p = 0.0002), penumbra evaluation (CT, 696.2 ± 52.7 s; MRI, 262.1 ± 9.3 s; p = 0.0002), and brain artery evaluation (CT, 592.1 ± 32.3 s; MRI, 367.8 ± 8.3 s; p = 0.0002). The coefficient of variation (CV) was lower for MRI compared to CT, indicating less variability in examination times with MRI. This study demonstrates that MRI protocols, including perfusion imaging, can more rapidly visualize factors essential for MT decision-making and do not delay time to MT.
在急性缺血性卒中(AIS)中,需要尽可能缩短评估时间以减少机械取栓(MT)的时间。随着MRI重建技术的最新进展,MRI在AIS治疗计划的决策过程中也变得很有价值。在本研究中,我们通过体模模拟比较了我们的MRI方案与标准CT方案在评估AIS时的检查时间,以获得与治疗策略直接相关的时间信息,并评估MRI在MT中的效用。十名放射技师对每种模式使用相同的体模进行扫描。评估项目包括出血检测时间、半暗带评估时间、脑动脉评估时间和总检查时间。与MRI(701.8±15.8秒)相比,CT的总检查时间略短(696.2±52.7秒),尽管这种差异无统计学意义(p = 0.4)。对于其他参数,MRI显示出明显更快的检测时间:出血检测(CT,80.9±12.8秒;MRI,66.3±1.7秒;p = 0.0002)、半暗带评估(CT,696.2±52.7秒;MRI,262.1±9.3秒;p = 0.0002)和脑动脉评估(CT,592.1±32.3秒;MRI,367.8±8.3秒;p = 0.0002)。与CT相比,MRI的变异系数(CV)更低,表明MRI检查时间的变异性更小。本研究表明,包括灌注成像在内的MRI方案可以更快地显示MT决策所需的关键因素,且不会延迟MT时间。