2025年4月，瑞典一名患者体内发现新型甲型（H1N2）季节性重组流感病毒。

Novel influenza A(H1N2) seasonal reassortant virus identified in a patient, Sweden, April 2025.

作者信息

Ujvari Dorina, Samuelsson Hagey Tove, Carnahan AnnaSara, Latorre-Margalef Neus

机构信息

Unit for Laboratory Surveillance of Viral Pathogens and Vaccine Preventable Diseases, National Influenza Center, Department of Microbiology, The Public Health Agency of Sweden, Solna, Sweden.

Unit for Coordination and Surveillance of Seasonal Viruses, Department of Communicable Disease Control and Health Protection, The Public Health Agency of Sweden, Solna, Sweden.

出版信息

Euro Surveill. 2025 Aug;30(31). doi: 10.2807/1560-7917.ES.2025.30.31.2500542.

DOI:10.2807/1560-7917.ES.2025.30.31.2500542

PMID:40776897

Abstract

In April 2025, a human seasonal reassortant influenza A(H1N2) virus with a 7:1 genetic constellation was detected in Sweden in a patient seeking primary care for influenza-like illness. The neuraminidase gene of this virus was from A(H3N2) and the remaining genes from A(H1N1)pdm09. The patient recovered. No additional cases have been detected through routine surveillance. This is so far the only identified A(H1N2) reassortant among three seasonal A(H1N1)pdm09 and A(H3N2) reassortants reported in GISAID from Europe during the 2024/25 season.

摘要

2025年4月，瑞典在一名因流感样疾病寻求初级医疗护理的患者身上检测到一种具有7:1基因组合的人类季节性重组甲型流感病毒A(H1N2)。该病毒的神经氨酸酶基因来自A(H3N2)，其余基因来自A(H1N1)pdm09。患者已康复。通过常规监测未检测到其他病例。这是2024/25季节欧洲在GISAID报告的三种季节性A(H1N1)pdm09和A(H3N2)重组病毒中迄今唯一确定的A(H1N2)重组病毒。