Shared Experiences With Guidewire Application in Chronic Total Occlusion: Technological Advances and Clinical Implications.

Chronic total occlusion (CTO) poses a significant challenge in cardiovascular interventional therapy, owing to the complexity and difficulty involved, which limit the effectiveness of traditional treatment methods. Thus, innovative designs and application concepts of guidewires have expanded the possibilities for clinical intervention, resulting in significant improvements in treatment strategies for CTO. Recently, numerous studies have detailed the application experiences of various guidewires in CTO interventional therapy, including the performance characteristics, selection strategies, and differences in clinical outcomes. Nevertheless, despite these advancements, limitations remain in CTO treatment, such as low success rates and the risk of complications. Therefore, this article aims to review the current application experience of CTO guidewires. Moreover, by reviewing existing literature and summarizing clinical practices, this paper explores strategies to optimize guidewire selection and usage to enhance the success rate and safety of CTO interventional therapy and provide practical guidance for clinicians.