Awad Alkozi Hanan, Alshammeri Saleh
Department of Optometry, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.
PeerJ. 2025 Aug 4;13:e19801. doi: 10.7717/peerj.19801. eCollection 2025.
Optimal sleep is essential for maintaining physiological homeostasis, and its disruption is associated with numerous physical and mental health issues. Previous studies have linked poor sleep quality to ocular conditions such as dry eye. However, the relationship between sleep quality and vision-related quality of life remains underexplored. This study aimed to investigate the association between ocular surface health and sleep quality, and how both factors relate to vision-related quality of life.
Ethical approval was granted by the Deanship of Graduate Studies and Scientific Research at Qassim University (reference no. 21-20-09), and the study was conducted in accordance with the Declaration of Helsinki. Young adult participants completed three questionnaires: the Pittsburgh Sleep Quality Index, the National Eye Institute Visual Function Questionnaire, and the Ocular Surface Disease Index. Ocular surface assessments were conducted using the Keratograph 5M and the Schirmer test to measure tear production.
Analysis revealed significant correlations between ocular symptoms and vision-related quality of life (Spearman's r = 0.47, < 0.0001, = 93), sleep efficiency (r = 0.22, < 0.05, = 75), and sleep disturbances (r = 0.25, < 0.05, = 75). A significant negative correlation was also found between sleep quality and vision-related quality of life (r = -0.31, < 0.005, = 75). These findings highlight the impact of sleep quality on ocular health, particularly the ocular surface.
The results suggest a meaningful link between sleep quality, ocular surface health, and vision-related quality of life. Further research is needed to clarify the causal mechanisms and risk factors contributing to ocular discomfort and its effects on visual well-being.
最佳睡眠对于维持生理稳态至关重要，而睡眠中断与众多身心健康问题相关。先前的研究已将睡眠质量差与诸如干眼等眼部疾病联系起来。然而，睡眠质量与视力相关生活质量之间的关系仍未得到充分探索。本研究旨在调查眼表健康与睡眠质量之间的关联，以及这两个因素如何与视力相关生活质量相关。
本研究获得了卡西姆大学研究生研究与科研院长的伦理批准（参考编号：21 - 20 - 09），并按照《赫尔辛基宣言》进行。年轻成年参与者完成了三份问卷：匹兹堡睡眠质量指数、美国国立眼科研究所视觉功能问卷和眼表疾病指数。使用角膜地形图仪5M和泪液分泌试验进行眼表评估以测量泪液分泌。
分析显示眼部症状与视力相关生活质量（斯皮尔曼相关系数r = 0.47，P < 0.0001，n = 93）、睡眠效率（r = 0.22，P < 0.05，n = 75）以及睡眠障碍（r = 0.25，P < 0.05，n = 75）之间存在显著相关性。睡眠质量与视力相关生活质量之间也发现了显著的负相关（r = -0.31，P < 0.005，n = 75）。这些发现突出了睡眠质量对眼部健康，尤其是眼表的影响。
结果表明睡眠质量、眼表健康与视力相关生活质量之间存在有意义的联系。需要进一步研究以阐明导致眼部不适及其对视觉健康影响的因果机制和风险因素。
