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伊拉克患者抗生素使用及耐药情况的患病率与模式:一项横断面研究。

Prevalence and pattern of antibiotic use and resistance among Iraqi patients: a cross-sectional study.

作者信息

Hashim Hashim Talib, Hashim Ali Talib, Ali Hossam Tharwat, Mohamed Haya, Elrefaey Ahmed, Almamoury Ameer, Aji Narjiss

机构信息

University of Baghdad, College of Medicine, Baghdad, Iraq.

Golestan University for Medical Sciences, Gorgan, Iran.

出版信息

Afr Health Sci. 2024 Sep;24(3):47-57. doi: 10.4314/ahs.v24i3.7.

Abstract

BACKGROUND

According to The Centers for Disease Control and Prevention (CDC) 2019, around 32,000 deaths in addition 2.8 million infections occur annually in the US because of antibiotic-resistant bacteria.

OBJECTIVES

To determine the prevalence and study pattern of antibiotic use and resistance among Iraqi patients.

METHODOLOGY

We carried out a cross-sectional study from January 2021 to October 2022 including data of 850 patients at different private and general hospitals, primary health centers, and private clinics. The data was collected during the patient's admission or visiting time using medical records and mini-interviews.

RESULTS

and were the most detected pathogens in our sample in 14.5% and 11.29% of the patients respectively. Most patients (87.18%) had taken over-the-counter antibiotics previously. Around 55% of the antibiotics that were tested were resisted among our patients who were included in 2021. This percentage has increased to about 75% of the included patients in 2022. Amoxicillin was the most resistant antibiotic (77%) in our sample while meropenem was the least resistant among the tested antibiotic (5%).

CONCLUSION

Antibiotic resistance is a major public health concern that is often caused by the overuse and misuse of antibiotics, as well as poor infection control practices.

摘要

背景

根据美国疾病控制与预防中心(CDC)2019年的数据,在美国,每年因抗生素耐药菌导致约3.2万人死亡,另外还有280万人感染。

目的

确定伊拉克患者中抗生素使用和耐药性的流行情况及研究模式。

方法

我们在2021年1月至2022年10月期间开展了一项横断面研究,纳入了不同私立和综合医院、初级卫生保健中心及私人诊所的850名患者的数据。数据是在患者入院或就诊时通过病历和小型访谈收集的。

结果

[此处原文缺失具体病原体名称]分别是我们样本中检出率最高的病原体,在患者中的占比分别为14.5%和11.29%。大多数患者(87.18%)此前服用过非处方抗生素。在我们纳入的2021年的患者中,约55%的检测抗生素存在耐药情况。到2022年,这一比例在纳入患者中增至约75%。在我们的样本中,阿莫西林是耐药性最高的抗生素(77%),而美罗培南是检测抗生素中耐药性最低的(5%)。

结论

抗生素耐药性是一个重大的公共卫生问题,通常是由抗生素过度使用和滥用以及感染控制措施不力所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e0/12327103/5eab421b9243/AFHS2403-0047Fig1.jpg

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