Fu Elise, Zhou Haoyin, de la Lastra Ángela Alarcón, Zhang Ruisi, Ayyala Haripriya, Broyles Justin, Pomahac Bohdan, Jagadeesan Jayender
Department of Radiology, Harvard Medical School, Boston, MA 02115 USA.
Smilow Cancer Hospital, Yale Medical School, New Haven, CT 06511.
IEEE Trans Med Robot Bionics. 2024 Nov;6(4):1345-1353. doi: 10.1109/tmrb.2024.3464739. Epub 2024 Sep 20.
Mastectomy is often coupled with breast reconstruction surgery (BRS) to reconstruct the breast mound. However, BRS is challenging and subject to the judgement of the surgeon in determining the amount of tissue to be harvested and the shape of reconstructed breast. To date, the existing tools aimed at maintaining symmetry and appearance of the reconstructed breast are costly. In this paper, we have developed an intuitive breast reconstruction system comprising a software application integrated with the simultaneous localization and mapping (SLAM) algorithm, and a low-cost RGB-D camera. Our SLAM-based breast reconstruction system will be used to scan and reconstruct the patient's breast using our customized mesh-generating method prior to mastectomy. Using this reconstructed model, a patient-specific 3D printed mold is created to help shape the harvested tissue that is inserted into the mastectomy site during BRS. Validation experiments show that the mean repeatability and accuracy errors for the surface reconstruction are less than 1.5 mm. The software application has been tested on 20 patients under an IRB-approved protocol including intraoperative guidance for 4 patients. The results show the consistent and accurate reconstruction of the breasts including the inframammary fold for different breast shapes and skin tones.
乳房切除术通常与乳房重建手术(BRS)相结合以重建乳房隆起。然而,乳房重建手术具有挑战性,并且在确定要采集的组织量和重建乳房的形状方面取决于外科医生的判断。迄今为止,旨在保持重建乳房的对称性和外观的现有工具成本高昂。在本文中,我们开发了一种直观的乳房重建系统,该系统包括一个与同步定位与地图构建(SLAM)算法集成的软件应用程序以及一台低成本的RGB-D相机。我们基于SLAM的乳房重建系统将在乳房切除术之前使用我们定制的网格生成方法来扫描和重建患者的乳房。使用这个重建模型,创建一个患者特定的3D打印模具,以帮助塑造在乳房重建手术期间插入乳房切除部位的采集组织的形状。验证实验表明,表面重建的平均重复性和准确性误差小于1.5毫米。该软件应用程序已在20名患者身上按照机构审查委员会批准的方案进行了测试,其中包括对4名患者的术中指导。结果显示,对于不同乳房形状和肤色的乳房,包括乳房下皱襞在内,都能进行一致且准确的重建。