Domingues Erik
Dr. Domingues is with Modern Dermatology of Massachusetts in Fall River, Massachusetts and the Department of Dermatology at the University of Massachusetts Chan Medical School in Worcester, Massachusetts.
J Clin Aesthet Dermatol. 2025 Jul 1;18(7):24-25.
Scalp psoriasis is a chronic immune skin disease affecting up to 80 percent of patients with psoriasis. Treatments include topical steroids, keratolytics, tar, anthralin, vitamin D analogs, and retinoids. However, treatment can be difficult due to the presence of hair. Roflumilast 0.3% cream was approved in 2022 for the treatment of chronic plaque psoriasis, including intertriginous areas. Here, we present the case of a 28-year-old female patient with scalp psoriasis, who had previously trialed both topical and systemic treatments for her disease without success. Use of once daily roflumilast 0.3% cream resulted in rapid scalp psoriasis clearance, with results seen as early as Day 3 and complete clearance by Day 5 of treatment without adverse events or tolerability concerns.
头皮银屑病是一种慢性免疫性皮肤病，高达80%的银屑病患者会受到影响。治疗方法包括外用类固醇、角质剥脱剂、焦油、蒽林、维生素D类似物和维甲酸。然而，由于有头发，治疗可能会很困难。0.3%的罗氟司特乳膏于2022年获批用于治疗慢性斑块状银屑病，包括间擦部位。在此，我们报告一例28岁头皮银屑病女性患者的病例，该患者此前曾尝试过局部和全身治疗，但均未成功。每天使用一次0.3%的罗氟司特乳膏可使头皮银屑病迅速清除，早在治疗第3天就可见到效果，到治疗第5天完全清除，且无不良事件或耐受性问题。
