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机械心脏瓣膜与妊娠

Mechanical heart valves and pregnancy.

作者信息

Kelly Bronagh, Walker Niki

机构信息

Scottish Adult Congenital Cardiac Service, Golden Jubilee National Hospital, Clydebank, G81 4DY, UK.

出版信息

JRSM Cardiovasc Dis. 2025 Aug 6;14:20480040251365987. doi: 10.1177/20480040251365987. eCollection 2025 Jan-Dec.

DOI:10.1177/20480040251365987
PMID:40778399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12329187/
Abstract

Pregnancy is an exciting time, with great anticipation of the future for the woman and her baby. However, for women with mechanical heart valves (MHVs) pregnancy is a challenging undertaking fraught with risk to them and their baby. This article considers the issues for the woman, highlighting pre-surgical opportunities, pre-pregnancy counselling, the issues to consider with fertility treatment, the options during pregnancy for anti-coagulation management and the recognition and management of complications. This update stresses the complex challenges in the management of women with MHV during pregnancy and the need for specialist multi-disciplinary team involvement.

摘要

怀孕是一段令人兴奋的时光,女性及其腹中胎儿都对未来满怀期待。然而,对于患有机械心脏瓣膜(MHV)的女性来说,怀孕是一项充满挑战的任务,对她们自身以及腹中胎儿都存在诸多风险。本文探讨了这类女性面临的问题,重点介绍了手术前的时机、孕前咨询、生育治疗时需考虑的问题、孕期抗凝管理的选择以及并发症的识别与管理。此次更新强调了孕期患有机械心脏瓣膜女性管理方面的复杂挑战,以及多学科专家团队参与的必要性。

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本文引用的文献

1
Anticoagulant Therapy in Pregnant Women with Mechanical Heart Valves: Italian Federation of Centers for Diagnosis and Surveillance of the Antithrombotic Therapies (FCSA) Position Paper.《机械心脏瓣膜孕妇抗凝治疗:意大利诊断和抗血栓治疗监测中心联合会(FCSA)立场文件》。
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Valvular Heart Disease in Pregnancy.妊娠期心脏瓣膜病。
Methodist Debakey Cardiovasc J. 2024 Mar 14;20(2):13-23. doi: 10.14797/mdcvj.1323. eCollection 2024.
3
Best practice recommendations for medically assisted reproduction in patients with known cardiovascular disease or at high risk of cardiovascular disease.已知患有心血管疾病或有心血管疾病高风险患者的医学辅助生殖最佳实践建议。
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4
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Br J Haematol. 2023 Aug;202(3):465-478. doi: 10.1111/bjh.18781. Epub 2023 Apr 1.
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Maternal and Fetal Outcomes in Pregnant Patients With Mechanical and Bioprosthetic Heart Valves.患有机械和生物心脏瓣膜的孕妇的母婴结局。
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Risk of Congenital Heart Defects in Offspring of Affected Mothers and Fathers.患儿父母所生孩子患先天性心脏缺陷的风险。
Circ Genom Precis Med. 2022 Aug;15(4):e003533. doi: 10.1161/CIRCGEN.121.003533. Epub 2022 May 24.
9
Mechanical heart valves and pregnancy: Issues surrounding anticoagulation. Experience from two obstetric cardiac centres.机械心脏瓣膜与妊娠:抗凝相关问题。来自两个产科心脏中心的经验。
Obstet Med. 2021 Jun;14(2):95-101. doi: 10.1177/1753495X20924937. Epub 2020 Jun 2.
10
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2020 ACC/AHA 瓣膜性心脏病患者管理指南:执行摘要:美国心脏病学会/美国心脏协会联合临床实践指南委员会的报告。
Circulation. 2021 Feb 2;143(5):e35-e71. doi: 10.1161/CIR.0000000000000932. Epub 2020 Dec 17.