Zhu Zhankun, Gao Guosheng, Hu Yaoren, Zhao Xiansheng
General Affairs Department, Ningbo No.2 Hospital, Ningbo, China.
Department of Clinical Laboratory, Ningbo No.2 Hospital, Ningbo, China.
PLoS One. 2025 Aug 8;20(8):e0328154. doi: 10.1371/journal.pone.0328154. eCollection 2025.
The ongoing COVID-19 pandemic underscores the necessity of understanding the transmission dynamics in enclosed, high-risk environments, such as clinic waiting rooms. This study used computational fluid dynamics (CFD) to investigate the behavior of virus-laden aerosols in clinic waiting rooms under six different scenarios with various temperatures and ventilation setups, offering insights into practical strategies for enhancing safety in healthcare environments. Key findings demonstrated that effective ventilation, through open windows and mechanical systems, can reduce virus-laden aerosol concentrations by up to 99.3% under optimal conditions (e.g., from 5.80 kg/m3 to 0.04 kg/m3By contrast, poorly ventilated scenarios exhibit significantly higher viral concentrations, which can rise as high as 5.80 kg/m3. A novel aspect of this research lies in the comprehensive modeling of human anatomy and aerosol interactions, which enhances the accuracy of viral-trajectory predictions. The practical implications include strategic recommendations for ventilation system design to mitigate transmission risks in clinical settings. These insights provide guidelines for healthcare facility design and emphasize the critical role of environmental control in reducing exposure to airborne pathogens.
持续的新冠疫情凸显了了解封闭的高风险环境(如诊所候诊室)中传播动态的必要性。本研究使用计算流体动力学(CFD)来调查在六种不同场景下,不同温度和通风设置的诊所候诊室中载有病毒的气溶胶的行为,为提高医疗环境安全性的实际策略提供见解。主要研究结果表明,通过打开窗户和机械系统进行有效通风,在最佳条件下(例如,从5.80千克/立方米降至0.04千克/立方米)可将载有病毒的气溶胶浓度降低高达99.3%。相比之下,通风不良的场景中病毒浓度显著更高,可高达5.80千克/立方米。这项研究的一个新颖之处在于对人体解剖结构和气溶胶相互作用进行了全面建模,提高了病毒轨迹预测的准确性。实际意义包括为通风系统设计提供战略建议,以降低临床环境中的传播风险。这些见解为医疗机构设计提供了指导方针,并强调了环境控制在减少空气传播病原体暴露方面的关键作用。