Kuhlman D S, Hodge S J, Owen L G
J Am Acad Dermatol. 1985 Oct;13(4):596-8. doi: 10.1016/s0190-9622(85)70203-4.
Hyperkeratosis of the nipple and areola is a rare condition. We report two cases of hyperkeratosis of the nipple and areola occurring in men with no underlying endocrinopathy or synthetic estrogenic drug therapy. Both patients demonstrated prompt resolution of the hyperkeratosis of the nipples with a keratolytic gel. Because our cases were not associated with ichthyosis or epidermal nevus, they best fit into the category of nevoid hyperkeratosis of the nipples.
乳头和乳晕角化过度是一种罕见的病症。我们报告两例发生在男性身上的乳头和乳晕角化过度病例，这些男性没有潜在的内分泌病或合成雌激素药物治疗史。两名患者使用角质溶解凝胶后，乳头角化过度症状均迅速缓解。由于我们的病例与鱼鳞病或表皮痣无关，它们最符合乳头痣样角化过度的类别。
