Anos Amr Mohammed Hamza, Wassef Nancy Zk
Gloucestershire Hospitals Foundation Trust, Cheltenham, United Kingdom.
Gloucestershire Hospitals Foundation Trust, Cheltenham, United Kingdom.
JACC Case Rep. 2025 Aug 6;30(22):104498. doi: 10.1016/j.jaccas.2025.104498.
Anomalous origin of the left main coronary artery from the right sinus of Valsalva (ALCA-RSV) is exceedingly rare yet complicates emergency angioplasty for ST-segment elevation myocardial infarction.
We describe 2 ST-segment elevation myocardial infarction patients in whom ALCA-RSV was identified during primary percutaneous coronary intervention. Despite procedural challenges, timely revascularization was achieved using customized access, catheter strategies, and adjunctive devices. Postprocedural computed tomography coronary angiography excluded malignant courses. Both patients achieved positive outcomes.
ALCA-RSV, while exceptionally uncommon, is associated with sudden cardiac death and procedural difficulties during percutaneous coronary intervention. Early identification, precise anatomical imaging, and adaptable techniques are key to successful management. This series contributes to limited existing literature, underscoring that favorable results are possible with tailored intervention strategies.
TAKE-HOME MESSAGES: ALCA-RSV complicates emergency angioplasty and necessitates adjusted strategies to achieve revascularization. Multimodality imaging aids risk assessment and delineates malignant from benign courses.
左冠状动脉起源于右冠状动脉窦(ALCA-RSV)极为罕见,但会使ST段抬高型心肌梗死的急诊血管成形术变得复杂。
我们描述了2例ST段抬高型心肌梗死患者,在初次经皮冠状动脉介入治疗期间发现了ALCA-RSV。尽管手术过程中存在挑战,但通过定制的入路、导管策略和辅助装置实现了及时的血管重建。术后计算机断层扫描冠状动脉造影排除了恶性走行。两名患者均取得了良好的结果。
ALCA-RSV虽然极为罕见,但与心脏性猝死和经皮冠状动脉介入治疗期间的手术困难有关。早期识别、精确的解剖成像和适应性技术是成功治疗的关键。本系列研究为有限的现有文献做出了贡献,强调了采用量身定制的干预策略可能会取得良好的结果。
ALCA-RSV会使急诊血管成形术变得复杂,需要调整策略以实现血管重建。多模态成像有助于风险评估,并区分恶性和良性走行。