Aronson P J, Fretzin D F, Potter B S
J Cutan Pathol. 1985 Dec;12(6):506-19. doi: 10.1111/j.1600-0560.1985.tb00450.x.
A patient presented with a frontal nodule of the scalp. Histopathological examination revealed a myxomatous multilobulate tumor composed of epithelioid cells with variable pleomorphism. Perineurium-like structures were seen but only around isolated lobules located at the tumor periphery. Electron microscopy revealed polygonal cells and cells with elongated cytoplasmic processes. Many cells had myelinoid figures. A basement membrane-like lamina was noted around some cells. Some of the tumor cells were immunoreactive for myelin basic protein. This finding suggests that the tumor cells are of schwannian type. Neurothekeoma of Gallager and Helwig is a rare, probably benign tumor with fairly distinctive histopathologic characteristics. It appears to be a variant of dermal nerve-sheath myxoma.
一名患者出现头皮前部结节。组织病理学检查显示为黏液样多叶状肿瘤，由具有不同程度多形性的上皮样细胞组成。可见类似神经束膜的结构，但仅见于肿瘤周边孤立小叶周围。电子显微镜检查显示多边形细胞和具有细长胞质突起的细胞。许多细胞有髓鞘样结构。在一些细胞周围可见类似基底膜的薄片。部分肿瘤细胞对髓鞘碱性蛋白呈免疫反应阳性。这一发现提示肿瘤细胞为雪旺氏细胞类型。Gallager和Helwig的神经鞘黏液瘤是一种罕见的、可能为良性的肿瘤，具有相当独特的组织病理学特征。它似乎是真皮神经鞘黏液瘤的一种变体。
