Lampe Elizabeth W, Crochiere Rebecca J, Moussaoui Jannah R, Martin Caroline, Crisp Destiny, Kim Ashley, Juarascio Adrienne S, Manasse Stephanie M
Center for Weight, Eating, and Lifestyle Science, Drexel University, Philadelphia, PA, USA; Department of Psychological & Brain Sciences, Drexel University, Philadelphia, PA, USA.
Department of Psychology, Williams College, Williamstown, MA, USA.
Appetite. 2025 Aug 7;216:108261. doi: 10.1016/j.appet.2025.108261.
Sleep disturbance has been linked with both increased negative affect and engagement in binge-eating (BE; i.e., eating episodes accompanied by a subjective sense of loss-of-control over eating). Negative affect itself is also predictive of BE. As such, it is possible that the effect of sleep disturbance on BE can be explained by increases in negative affect. We recruited adults with clinically significant BE (N = 96, M = 41.9 ± 14.1, 80.4 % female) to complete seven ecological momentary assessment surveys per day assessing sleep disturbance (morning surveys only), negative affect, and BE over 7-14 days. Mediation models evaluated whether there was an indirect effect of within-person increases in negative affect prior to binge eating on the association between within-person sleep disturbance (i.e., poor sleep quality, heightened morning fatigue, and short sleep duration relative to one's average) and binge eating. Pre-binge levels of negative affect mediated the association between both sleep quality (Est = -0.019, S.E. = 0.009, p = 0.028) and morning fatigue (Est = 0.020, S.E. = 0.009, p = 0.024) and BE. Negative affect did not significantly mediate the association between sleep duration and BE. Negative affect may be one mechanism linking sleep disturbance and BE. These findings suggest that treatments targeting sleep disturbance merit evaluation in eating disorder populations as they could eliminate sleep-related NA as a driver of BE. Future research should include objective assessment of sleep and test the additive benefit of interventions targeting sleep for BE.
睡眠障碍与负面影响增加以及暴饮暴食（即进食过程中伴有主观上对进食失去控制感的发作）都有关联。负面影响本身也可预测暴饮暴食。因此，睡眠障碍对暴饮暴食的影响可能可以通过负面影响的增加来解释。我们招募了患有具有临床意义的暴饮暴食症的成年人（N = 96，M = 41.9 ± 14.1，80.4%为女性），让他们每天完成七次生态瞬时评估调查，在7 - 14天内评估睡眠障碍（仅早晨调查）、负面影响和暴饮暴食情况。中介模型评估了在暴饮暴食之前，个体内部负面影响的增加对个体内部睡眠障碍（即睡眠质量差、早晨疲劳加剧以及相对于个人平均水平的睡眠时间短）与暴饮暴食之间关联是否存在间接影响。暴饮暴食前的负面影响水平介导了睡眠质量（估计值 = -0.019，标准误 = 0.009，p = 0.028）和早晨疲劳（估计值 = 0.020，标准误 = 0.009，p = 0.024）与暴饮暴食之间的关联。负面影响并未显著介导睡眠时间与暴饮暴食之间的关联。负面影响可能是连接睡眠障碍和暴饮暴食的一种机制。这些发现表明，针对睡眠障碍的治疗方法值得在饮食失调人群中进行评估，因为它们可以消除与睡眠相关的负面影响这一暴饮暴食的驱动因素。未来的研究应包括对睡眠的客观评估，并测试针对暴饮暴食的睡眠干预措施的附加益处。
