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在现场条件下对尿液中氨苯砜进行血凝抑制试验的应用。

Application of HI test for dapsone in urine under field conditions.

作者信息

de Wit M, Balakrishnan S, Kumar A

出版信息

Indian J Lepr. 1985 Apr-Jun;57(2):318-22.

PMID:4078357
Abstract

One hundred and two specimens of urine collected from leprosy patients attending the field clinics of Central Leprosy Teaching and Research Institute, Chingleput, Tamil Nadu, India, were screened for dapsone by the paper spot test and Haemagglutination Inhibition (HI) tests. A concordance of about 90% was observed between the two tests. Both tests showed their merits. The lower sensitivity of the spot test finds more cases of irregular compliance (1-2 days), whereas the higher sensitivity of the HI allows the demonstration of the intake of lower doses and the detection of those cases, who have grossly missed their tablets (longer than a week).

摘要

从印度泰米尔纳德邦钦格利普特中央麻风病教学与研究所现场诊所的麻风病患者中收集了102份尿液样本,通过纸片斑点试验和血凝抑制(HI)试验对其中的氨苯砜进行筛查。两种试验之间的一致性约为90%。两种试验都显示出了各自的优点。斑点试验较低的灵敏度能发现更多不规律服药(1 - 2天)的病例,而HI试验较高的灵敏度则能显示较低剂量药物的摄入情况,并检测出那些严重漏服药物(超过一周)的病例。

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Indian J Lepr. 1985 Apr-Jun;57(2):318-22.
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