Jesudasan K, Bradley D, Christian M
Indian J Lepr. 1985 Apr-Jun;57(2):354-9.
This study examined the risk of relapse in 421 paucibacillary patients who had defaulted after varying periods of dapsone monotherapy; short of the recommended course. The 421 patients contributed a total of 2,162 person years of risk; 10 patients relapsed, giving a relapse rate of 4.6 per 1000 persons years of risk, or a crude relapse rate (RR) of 2.4%. This paper discusses the issue of defaulters with paucibacillary leprosy and the findings of the study suggest that defaulters with paucibacillary leprosy are not a serious problem in terms of leprosy control.
本研究调查了421例少菌型患者在接受不同疗程的氨苯砜单药治疗(未达推荐疗程)后复发的风险。这421例患者共产生了2162人年的风险;其中10例复发,复发率为每1000人年风险中有4.6例,即粗复发率(RR)为2.4%。本文讨论了少菌型麻风病患者中断治疗的问题,研究结果表明,就麻风病控制而言,少菌型麻风病患者中断治疗并非严重问题。