Jung Mary, Tran Duong, Chang Chi-Ching, Kim Sung K, Tsukiboshi Yosuke, Min Seiko, Ayilavarapu Srinivas, Lee Chun-Teh
Department of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
J Periodontol. 2025 Aug 10. doi: 10.1002/jper.11381.
This study is part of a randomized controlled trial investigating the impact of soft tissue augmentation (STA) using subepithelial connective tissue graft (SCTG) (immediate implant with subepithelial connective tissue graft [ICT] group) or acellular dermal matrix (ADM) (immediate implant with acellular dermal matrix [IAD] group) versus no STA (control) on the clinical outcomes following immediate implant placement (IIP). This study aimed to investigate volumetric buccal bone dimensional changes at immediate implant sites 6 months after the surgery.
Forty-five patients requiring extraction of a maxillary anterior tooth or premolar and randomly assigned to one of the three groups were included. Cone-beam computed tomography (CBCT) images were obtained prior to tooth extraction and 6 months after IIP and then superimposed to evaluate 3D (volumetric) and 2D (linear) changes in buccal bone dimensions around the implant. Measurements included three regions of interest (coronal, middle, and apical segments). The associations between clinical factors and 3D buccal bone dimensional changes were analyzed using linear regression analysis. The correlations between 3D and 2D measurements were analyzed using Pearson's correlation coefficient. Statistical significance was assessed using an alpha level of 0.05.
Volumetric bone dimensional changes were not significantly different between the groups. The greatest amount of bone loss occurred in the coronal segment (ICT: -14.99 ± 4.29 mm; IAD: -13.60 ± 3.97 mm; Control: -12.58 ± 4.09 mm; p = 0.286). The thick bone morphotype was significantly associated with increased absolute volumetric bone loss (p = 0.001, 0.041, and 0.013 for coronal, middle, and apical segments, respectively). Measurements of 3D and 2D bone dimensional changes had low to high correlations (range 0.39-0.95) in different segments.
STA did not significantly affect bone dimensional loss at 6 months. Linear measurements may not fully represent volumetric bone dimensional changes at immediate implant sites.
This study is part of a randomized controlled trial (RCT) registered with ClinicalTrials.gov (ID NCT02864862). The title of the trial is Esthetic Outcomes Following Immediate Implant Combined with Soft Tissue Augmentation.
This study investigated how soft tissue augmentation (STA) affected the changes in bone around dental implants placed immediately after tooth extraction. Specifically, it compared the use of a connective tissue graft and an acellular dermal matrix against no STA. Forty-five patients who needed a maxillary anterior tooth or premolar extraction and a dental implant were included. Before the extraction and 6 months after implant placement, cone-beam computed tomography (CBCT) scans were taken to measure changes in the bone dimensions around the implants. The analysis included three sections of the bone: the coronal, middle, and apical sections. The results showed no significant differences in bone changes between the different treatment groups. The greatest bone loss was found in the coronal section. Measurements taken in three dimensions (3D) and two dimensions (2D) showed varying degrees of correlation. Overall, the findings suggested that STA did not affect bone loss around dental implants, and 2D measurements may not accurately reflect the 3D changes in bone.
本研究是一项随机对照试验的一部分，该试验旨在研究使用上皮下结缔组织移植（SCTG）进行软组织增量（STA）（即刻种植联合上皮下结缔组织移植[ICT]组）或无细胞真皮基质（ADM）（即刻种植联合无细胞真皮基质[IAD]组）与不进行STA（对照组）对即刻种植（IIP）后临床结果的影响。本研究旨在调查术后6个月即刻种植部位颊侧骨体积的变化。
纳入45例需要拔除上颌前牙或前磨牙并随机分配至三组之一的患者。在拔牙前和即刻种植后6个月获取锥形束计算机断层扫描（CBCT）图像，然后进行叠加以评估种植体周围颊侧骨维度的三维（体积）和二维（线性）变化。测量包括三个感兴趣区域（冠段、中段和根尖段）。使用线性回归分析临床因素与三维颊侧骨维度变化之间的关联。使用Pearson相关系数分析三维和二维测量之间的相关性。使用α水平为0.05评估统计学显著性。
各组间骨体积维度变化无显著差异。最大骨吸收量发生在冠段（ICT组：-14.99±4.29mm；IAD组：-13.60±3.97mm；对照组：-12.58±4.09mm；p = 0.286）。厚骨形态型与绝对骨体积损失增加显著相关（冠段、中段和根尖段的p值分别为0.001、0.041和0.013）。不同节段的三维和二维骨维度变化测量具有低到高的相关性（范围为0.39 - 0.95）。
软组织增量在6个月时对骨维度损失无显著影响。线性测量可能无法完全代表即刻种植部位的骨体积维度变化。
本研究是一项在ClinicalTrials.gov注册的随机对照试验（RCT）的一部分（ID NCT02864862）。试验标题为即刻种植联合软组织增量后的美学效果。
本研究调查了软组织增量（STA）如何影响拔牙后即刻植入的牙种植体周围骨的变化。具体而言，它比较了使用结缔组织移植和无细胞真皮基质与不进行STA的情况。纳入了45例需要拔除上颌前牙或前磨牙并进行牙种植的患者。在拔牙前和种植后6个月，进行锥形束计算机断层扫描（CBCT）扫描以测量种植体周围骨维度的变化。分析包括骨的三个部分：冠段、中段和根尖段。结果显示不同治疗组之间的骨变化无显著差异。最大的骨吸收发生在冠段。三维（3D）和二维（2D）测量显示出不同程度的相关性。总体而言，研究结果表明STA不影响牙种植体周围的骨吸收，二维测量可能无法准确反映骨的三维变化。
