Lin Qian, Li Deyan, Li Yinzhen, Duan Hui, Tian Yang, Li Ke, Xie Jiazhong, Zhang Xueyin
Department of Imaging, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
Quant Imaging Med Surg. 2025 Aug 1;15(8):6959-6968. doi: 10.21037/qims-2025-406. Epub 2025 Jul 30.
Accurate visualization of small abdominal arteries is crucial for diagnosis, preoperative evaluation, and treatment planning, especially in hepatobiliary and pancreatic diseases. However, due to their small calibers and rapid contrast transit, consistent delineation of these vessels remains challenging in conventional computed tomography (CT) angiography. Recent advancements in image postprocessing, such as contrast enhancement boost (CE-Boost) techniques, offer opportunities to improve vascular conspicuity without additional radiation or contrast agent. This study aimed to evaluate the efficacy of CE-Boost technology in improving image quality and vascular delineation for small abdominal vessels in multiphase contrast-enhanced CT examinations.
This retrospective analysis included 100 patients undergoing triphasic abdominal CT between July to November 2024. Raw datasets were reconstructed using an adaptive iterative denoising algorithm to generate conventional images (Group A). Subsequent application of flexible subtraction CE-Boost technology produced optimized images (Group B). Quantitative analysis measured CT attenuation values and noise levels (standard deviation) in four arterial branches (common hepatic, left gastric, splenic, and superior mesenteric arteries) and adjacent erector spinae musculature. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated for vascular structures. Two blinded radiologists independently scored image quality using a 5-point Likert scale, with interobserver agreement assessed via Cohen's kappa.
CE-Boost-processed images (Group B) demonstrated significantly improved image quality compared to conventional processing (Group A). Quantitative analysis showed higher CT attenuation values in Group B across all evaluated arterial branches: common hepatic artery [median 362.50 256.00 Hounsfield units (HU), P<0.001], left gastric artery (333.87±77.27 230.38±53.90 HU, P<0.001), splenic artery (median 374.50 257.17 HU, P<0.001), and superior mesenteric artery (median 380.67 269.00 HU, P<0.001). Mean increases ranged from 48 to 62 HU. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) improved by 39-54% across target vessels (all P<0.001). Subjective scoring also favored Group B, with higher overall image quality scores {median: 5 [interquartile range (IQR): 4-5] 4 (IQR: 4-5), P<0.001}, and strong interobserver agreement (κ=0.776 for Group B, κ=0.723 for Group A, both P<0.001). These results indicate superior vascular enhancement and diagnostic visibility using CE-Boost processing.
CE-Boost technology significantly enhances the visualization of small abdominal vasculature through advanced postprocessing optimization. The technique improves objective image quality metrics (CT attenuation, SNR, CNR) while maintaining diagnostic noise levels, and demonstrates high clinical utility for vascular mapping. These advancements in image processing workflows may facilitate more accurate anatomical assessment and diagnostic interpretation of small vessel pathologies.
准确显示腹部小动脉对于诊断、术前评估和治疗规划至关重要,尤其是在肝胆胰疾病中。然而,由于这些血管管径小且造影剂通过迅速,在传统计算机断层扫描(CT)血管造影中,持续清晰地描绘这些血管仍然具有挑战性。图像后处理的最新进展,如对比增强提升(CE-Boost)技术,为在不增加辐射或造影剂的情况下提高血管清晰度提供了机会。本研究旨在评估CE-Boost技术在多期对比增强CT检查中改善腹部小血管图像质量和血管描绘的效果。
这项回顾性分析纳入了2024年7月至11月期间接受腹部三期CT检查的100例患者。使用自适应迭代去噪算法重建原始数据集以生成传统图像(A组)。随后应用灵活减法CE-Boost技术生成优化图像(B组)。定量分析测量了四条动脉分支(肝总动脉、胃左动脉、脾动脉和肠系膜上动脉)及相邻竖脊肌组织的CT衰减值和噪声水平(标准差)。计算血管结构的信噪比(SNR)和对比噪声比(CNR)。两名盲法放射科医生使用5分李克特量表对图像质量进行独立评分,通过科恩kappa系数评估观察者间的一致性。
与传统处理(A组)相比,CE-Boost处理的图像(B组)显示图像质量有显著改善。定量分析显示,B组所有评估的动脉分支的CT衰减值均较高:肝总动脉[中位数362.50对256.00亨氏单位(HU),P<0.001],胃左动脉(333.87±77.27对230.38±53.90 HU,P<0.001),脾动脉(中位数374.50对257.17 HU,P<0.001),肠系膜上动脉(中位数380.67对269.00 HU,P<0.001)。平均增加范围为48至62 HU。目标血管的信噪比(SNR)和对比噪声比(CNR)提高了39 - 54%(所有P<0.001)。主观评分也更倾向于B组,整体图像质量得分更高{中位数:5[四分位间距(IQR):4 - 5]对4(IQR:4 - 5),P<0.001},且观察者间一致性强(B组κ = 0.776,A组κ = 0.723,均P<0.001)。这些结果表明使用CE-Boost处理可实现更好的血管增强和诊断可视性。
CE-Boost技术通过先进的后处理优化显著增强了腹部小血管的可视化。该技术在保持诊断噪声水平的同时提高了客观图像质量指标(CT衰减、SNR、CNR),并在血管成像方面显示出较高的临床实用性。图像处理工作流程的这些进展可能有助于更准确地评估小血管病变的解剖结构和进行诊断解读。