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一名未修复的特雷彻-柯林斯综合征患儿的多学科气道管理及术后规划:病例报告

Multidisciplinary Airway Management and Postoperative Planning in a Pediatric Patient With Unrepaired Treacher-Collins Syndrome: A Case Report.

作者信息

Rein Lauren E, McQuitty Alexis, Nguyen Thong

机构信息

Anesthesiology, University of Texas Medical Branch at Galveston, Galveston, USA.

出版信息

Cureus. 2025 Jul 10;17(7):e87655. doi: 10.7759/cureus.87655. eCollection 2025 Jul.

DOI:10.7759/cureus.87655
PMID:40786330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12335011/
Abstract

Treacher-Collins syndrome (TCS) presents significant challenges in airway management due to craniofacial abnormalities that often worsen with age. We describe the anesthetic management of a three-year-old male with TCS and no history of corrective surgery. Ketamine was used to facilitate vascular access and achieve adequate anesthetic depth. After three unsuccessful intubation attempts, an adult-sized Ovassapian airway was employed to guide a fiberoptic bronchoscope beneath the epiglottis and through the vocal cords, resulting in successful intubation. Postoperative airway management was optimized through multidisciplinary collaboration, highlighting the importance of preoperative planning and team-based decision-making in complex pediatric airway cases.

摘要

由于颅面畸形通常会随着年龄增长而恶化,因此特雷彻-柯林斯综合征(TCS)在气道管理方面带来了重大挑战。我们描述了一名三岁男性TCS患者且无矫正手术史的麻醉管理情况。使用氯胺酮来促进血管穿刺并达到足够的麻醉深度。在三次插管尝试失败后,使用成人尺寸的奥瓦萨皮安气道引导纤维支气管镜到达会厌下方并穿过声带,从而成功插管。通过多学科协作优化了术后气道管理,突出了术前规划和基于团队的决策在复杂儿科气道病例中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9951/12335011/4cb58af2b70e/cureus-0017-00000087655-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9951/12335011/9ac051f2f3ed/cureus-0017-00000087655-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9951/12335011/4cb58af2b70e/cureus-0017-00000087655-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9951/12335011/9ac051f2f3ed/cureus-0017-00000087655-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9951/12335011/4cb58af2b70e/cureus-0017-00000087655-i02.jpg

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本文引用的文献

1
Severity of Mandibular Dysmorphology in Treacher Collins Syndrome for Stratification of Perioperative Airway Risk.特雷彻·柯林斯综合征下颌骨畸形严重程度与围手术期气道风险分层。
J Craniofac Surg. 2024;35(1):18-22. doi: 10.1097/SCS.0000000000009700. Epub 2023 Aug 30.
2
Craniofacial and Upper Airway Development in Patients With Treacher Collins Syndrome.特雷彻·柯林斯综合征患者的颅面和上呼吸道发育。
J Craniofac Surg. 2021 Oct 1;32(7):2305-2309. doi: 10.1097/SCS.0000000000007661.
3
Treacher Collins Mandibular Distraction.特雷彻·柯林斯下颌骨牵张术。
Clin Plast Surg. 2021 Jul;48(3):431-444. doi: 10.1016/j.cps.2021.02.005.
4
Treacher Collins Syndrome and Tracheostomy: Decannulation Using Mandibular Distraction Osteogenesis.特雷彻·柯林斯综合征与气管造口术:应用下颌骨牵张成骨术进行拔管
Ann Plast Surg. 2018 Sep;81(3):305-310. doi: 10.1097/SAP.0000000000001514.
5
Tracheostomy for Severe Pediatric Obstructive Sleep Apnea: Indications and Outcomes.小儿重度阻塞性睡眠呼吸暂停的气管切开术:适应证与治疗结果
Otolaryngol Head Neck Surg. 2017 Aug;157(2):309-313. doi: 10.1177/0194599817702369. Epub 2017 Apr 18.
6
Reduced three-dimensional airway volume is a function of skeletal dysmorphology in Treacher Collins syndrome.三维气道容积减小是特雷彻·柯林斯综合征骨骼形态异常的一个表现。
Plast Reconstr Surg. 2015 Feb;135(2):382e-392e. doi: 10.1097/PRS.0000000000000993.
7
Anesthesia for Treacher Collins syndrome: a review of airway management in 240 pediatric cases.特雷彻·柯林斯综合征的麻醉:240例儿科病例的气道管理综述
Paediatr Anaesth. 2012 Aug;22(8):752-8. doi: 10.1111/j.1460-9592.2012.03829.x. Epub 2012 Mar 7.
8
Treacher Collins syndrome: etiology, pathogenesis and prevention.特雷彻·柯林斯综合征:病因、发病机制与预防
Eur J Hum Genet. 2009 Mar;17(3):275-83. doi: 10.1038/ejhg.2008.221. Epub 2008 Dec 24.
9
Dexmedetomidine and ketamine for fiberoptic intubation in a child with severe mandibular hypoplasia.
J Clin Anesth. 2008 Sep;20(6):455-7. doi: 10.1016/j.jclinane.2008.03.012.