Zeen Al-Deen Aamer, Al-Hashimi Haitham, Baaj Basel, Siyagha Kasem, Roqia Salah Aldeen, Fatima Tasneem, Tabatabai Sadeq
Graduate Medical Education Department, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, ARE.
Cardiology Department, Rashid Hospital, Dubai Health, Dubai, ARE.
Cureus. 2025 Jul 9;17(7):e87576. doi: 10.7759/cureus.87576. eCollection 2025 Jul.
Background Coronary artery anomalies (CAAs) are uncommon congenital variations with potentially significant clinical implications, including myocardial ischemia and sudden cardiac death. Data on their prevalence and patterns in the United Arab Emirates (UAE), particularly in Dubai, remain limited. Objectives This study aimed to evaluate the prevalence, anatomical types, and clinical presentation of CAAs among patients undergoing coronary angiography at a tertiary care center in Dubai. Methods A retrospective analysis was conducted on all coronary angiograms performed at Rashid Hospital between January 1, 2017, and December 31, 2023. Two independent cardiologists reviewed the angiograms to identify CAAs. Clinical data, including presentation and left ventricular ejection fraction (LVEF), were extracted from electronic medical records. Results Among 6,228 coronary angiograms, 92 patients (1.48%) were found to have CAAs. Myocardial bridging was the most frequent anomaly (52.2%), followed by anomalies of coronary origin (45.7%) and coronary artery fistula (2.2%). The majority of patients were men (85.9%), with a mean age of 54.0 ± 11.5 years. Acute myocardial infarction (AMI) was the most common presentation (63.0%). Most patients had preserved left ventricular ejection fraction (67%) and were discharged alive (97.8%). AMI occurred more frequently in origin-related CAAs (73.8%), while anginal symptoms were more common in course-related CAAs (37.5% versus 14.3%, P = 0.086). Conclusion CAAs were infrequent but clinically relevant findings in patients undergoing coronary angiography in Dubai. Myocardial bridging was the predominant anomaly. These results underscore the importance of systematic evaluation for CAAs during angiographic assessment. Further multicenter research utilizing advanced imaging and long-term follow-up is needed to refine risk stratification and management strategies.
冠状动脉异常（CAAs）是罕见的先天性变异，具有潜在的重大临床意义，包括心肌缺血和心源性猝死。关于其在阿拉伯联合酋长国（UAE），尤其是在迪拜的患病率和模式的数据仍然有限。
本研究旨在评估迪拜一家三级医疗中心接受冠状动脉造影的患者中CAAs的患病率、解剖类型和临床表现。
对2017年1月1日至2023年12月31日在拉希德医院进行的所有冠状动脉造影进行回顾性分析。两名独立的心脏病专家对造影进行审查以识别CAAs。从电子病历中提取临床数据，包括临床表现和左心室射血分数（LVEF）。
在6228例冠状动脉造影中，92例患者（1.48%）被发现有CAAs。心肌桥是最常见的异常（52.2%），其次是冠状动脉起源异常（45.7%）和冠状动脉瘘（2.2%）。大多数患者为男性（85.9%），平均年龄为54.0±11.5岁。急性心肌梗死（AMI）是最常见的表现（63.0%）。大多数患者左心室射血分数保留（67%）且存活出院（97.8%）。AMI在起源相关的CAAs中更常见（73.8%），而心绞痛症状在走行相关的CAAs中更常见（37.5%对14.3%，P = 0.086）。
在迪拜接受冠状动脉造影的患者中，CAAs并不常见，但具有临床相关性。心肌桥是主要异常。这些结果强调了在血管造影评估期间对CAAs进行系统评估的重要性。需要利用先进成像和长期随访的进一步多中心研究来完善风险分层和管理策略。
