Jordán de Luna Consuelo, Esteve Gomez Anna, Montero Pérez Olalla, Clopés Estela Ana, Oliva Marc, Lozano Borbalas Alicia, Mesía Nin Riard
Pharmacy Department, Institut Català d'Oncologia-ICO, L'Hospitalet de Llobregat, Barcelona, Spain.
Department of Clinical Sciences, School of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.
Front Oncol. 2025 Jul 25;15:1598125. doi: 10.3389/fonc.2025.1598125. eCollection 2025.
The Catalan Institute of Oncology (ICO) is a comprehensive centre for the prevention, diagnosis, and treatment of cancer. At the institute, there is a set of institutional clinical practice guidelines, named ICOPraxis. The field of oncology therapeutics is currently undergoing a transition towards a model of personalised medicine. Institutional clinical guidelines can be more precise in their recommendations by providing a local focus. An evaluation of the utility of clinical guidelines may be conducted through a descriptive analysis of the selection of treatment and the resulting outcome. Retrospective cohort analysis of patients diagnosed with locally-advanced and recurrent/metastatic HNSCC (stage III to IVc according to 7 and 8th edition TNM-AJCC) and treated at the The Head and Neck Cancer Functional Unit of ICO and Bellvitge University Hospital. This study allows us to describe the outcomes of our head and neck tumour patients with real-life data providing information on the possible dilution of the effect when compared to reference clinical trials.
加泰罗尼亚肿瘤研究所（ICO）是一家癌症预防、诊断和治疗的综合中心。该研究所拥有一套名为ICOPraxis的机构临床实践指南。肿瘤治疗领域目前正朝着个性化医疗模式转变。机构临床指南通过提供本地重点，其建议可能会更加精确。可以通过对治疗选择和结果的描述性分析来评估临床指南的效用。对在ICO头颈癌功能单元和贝尔维奇大学医院接受治疗的局部晚期和复发/转移性头颈部鳞状细胞癌（根据第7版和第8版TNM-AJCC为III至IVc期）患者进行回顾性队列分析。这项研究使我们能够用实际数据描述头颈肿瘤患者的治疗结果，提供与参考临床试验相比可能存在的效果稀释信息。
