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一名唇腭裂患者在二次骨移植7年后被诊断出鼻腭管囊肿的罕见病例。

A Rare Case of Nasopalatine Duct Cyst Diagnosed 7 Years After Secondary Bone Grafting in a Patient With Cleft Lip and Palate.

作者信息

Yusa Kazuyuki, Kasuya Satoshi, Sasahara Nobuyuki, Hemmi Tomoharu, Ishikawa Shigeo

机构信息

Department of Dentistry, Oral and Maxillofacial-Plastic and Reconstructive Surgery Faculty of Medicine, Yamagata University, Yamagata, Japan.

出版信息

Case Rep Dent. 2025 Aug 2;2025:5520791. doi: 10.1155/crid/5520791. eCollection 2025.

DOI:10.1155/crid/5520791
PMID:40786704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12335353/
Abstract

Secondary autogenous particulate cancellous bone and marrow grafting (SBG) is a reliable and established technique for patients with alveolar cleft. Some reports have described complications after SBG, but cyst formation in alveolar bone where SBG has been performed appears to be extremely rare. Herein, we report a rare case of a cyst forming at a grafted site 5 years after SBG. A 15-year-old girl was referred to our clinic with a chief complaint of swelling in the right maxilla. The patient had a history of multiple surgeries for cleft lip and palate. Panoramic radiography and computed tomography (CT) revealed a radiolucency in the right maxilla, at the site where SBG had been performed. Enucleation of the lesion and bone graft using particulate cancellous bone and marrow were performed. The histological diagnosis was a nasopalatine duct cyst. Postoperatively, no signs of recurrence have been observed. Some reports have suggested that damage to the incisive canal can lead to the formation of nasopalatine duct cysts. SBG thus needs to be performed with care, as invasion of the incisive canal during the procedure may result in cyst formation and the need for additional surgery.

摘要

二期自体颗粒松质骨和骨髓移植(SBG)是治疗牙槽嵴裂患者的一种可靠且成熟的技术。一些报告描述了SBG术后的并发症,但在进行过SBG的牙槽骨中形成囊肿的情况似乎极为罕见。在此,我们报告一例在SBG术后5年移植部位形成囊肿的罕见病例。一名15岁女孩因右侧上颌肿胀为主诉前来我院就诊。该患者有唇腭裂多次手术史。全景X线片和计算机断层扫描(CT)显示右侧上颌在进行SBG的部位有透光区。对病变进行了摘除,并使用颗粒松质骨和骨髓进行了骨移植。组织学诊断为鼻腭管囊肿。术后未观察到复发迹象。一些报告表明,切牙管损伤可导致鼻腭管囊肿形成。因此,进行SBG时需要谨慎,因为手术过程中对切牙管的侵犯可能导致囊肿形成以及需要额外的手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/96fa48f67da7/CRID2025-5520791.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/8034de0b46a5/CRID2025-5520791.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/f2c26439fa50/CRID2025-5520791.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/1ad8f6369eea/CRID2025-5520791.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/96fa48f67da7/CRID2025-5520791.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/8034de0b46a5/CRID2025-5520791.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/f2c26439fa50/CRID2025-5520791.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/1ad8f6369eea/CRID2025-5520791.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d8/12335353/96fa48f67da7/CRID2025-5520791.004.jpg

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本文引用的文献

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Nasopalatine duct cyst.鼻腭管囊肿
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