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肠淋巴管扩张症:胃肠道出血的一种罕见病因。

Intestinal Lymphangiectasia: A Rare Etiology of Gastrointestinal Bleeding.

作者信息

Baghi Mohamed A, Hamid Abdulwahab, Badi Ahmed Mohamed, Al-Mohannadi Muneera Jassim

机构信息

General Internal Medicine Hamad Medical Corporation Doha Qatar.

Qatar University College of Medicine (QU) Doha Qatar.

出版信息

Clin Case Rep. 2025 Aug 7;13(8):e70637. doi: 10.1002/ccr3.70637. eCollection 2025 Aug.

DOI:10.1002/ccr3.70637
PMID:40787167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12331520/
Abstract

Intestinal lymphangiectasia (IL) is a rare condition characterized by the blockage of lymphatic fluid draining from the small intestine. It commonly presents with symptoms such as malabsorption, diarrhea, and hypoproteinemia. Bleeding from IL is an infrequent manifestation. We report a rare case of bleeding intestinal lymphangiectasia in a patient who presented with symptomatic anemia and melena. Enteroscopy identified a focal mucosal lesion without active bleeding, while video capsule endoscopy revealed a mucosal lesion with active blood oozing in the proximal jejunum. Subsequent biopsy results confirmed focal lymphangiectasia with vascular congestion. The patient underwent laparoscopic resection of the jejunal lesion. Follow-up evaluations at 3 and 6 months showed no recurrence of symptoms.

摘要

肠淋巴管扩张症(IL)是一种罕见疾病,其特征为从小肠引流的淋巴液受阻。它通常表现为吸收不良、腹泻和低蛋白血症等症状。IL出血是一种不常见的表现。我们报告一例罕见的出血性肠淋巴管扩张症病例,该患者表现为症状性贫血和黑便。小肠镜检查发现一处无活动性出血的局灶性黏膜病变,而视频胶囊内镜检查显示空肠近端有一处黏膜病变伴有活动性渗血。随后的活检结果证实为局灶性淋巴管扩张症伴血管充血。该患者接受了空肠病变的腹腔镜切除术。3个月和6个月的随访评估显示症状未复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/7e5c159a2080/CCR3-13-e70637-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/b3583c892eaa/CCR3-13-e70637-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/b553819af7c6/CCR3-13-e70637-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/7e5c159a2080/CCR3-13-e70637-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/b3583c892eaa/CCR3-13-e70637-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/b553819af7c6/CCR3-13-e70637-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04e/12331520/7e5c159a2080/CCR3-13-e70637-g001.jpg

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本文引用的文献

1
Pathophysiology, Diagnosis, and Management of Canine Intestinal Lymphangiectasia: A Comparative Review.犬肠道淋巴管扩张症的病理生理学、诊断与管理:一项比较性综述
Animals (Basel). 2022 Oct 15;12(20):2791. doi: 10.3390/ani12202791.
2
Sticky Situation: Bleeding Duodenal Lymphangiectasias Treated with Lymphatic Glue Embolization.棘手情况:采用淋巴管胶水栓塞术治疗十二指肠淋巴管扩张症伴出血
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Ileal polypoid lymphangiectasia bleeding diagnosed and treated by double balloon enteroscopy.
经双气囊小肠镜诊断和治疗的回肠息肉样淋巴管扩张出血。
World J Gastroenterol. 2013 Dec 7;19(45):8440-4. doi: 10.3748/wjg.v19.i45.8440.
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World J Gastroenterol. 2007 Apr 21;13(15):2263-5. doi: 10.3748/wjg.v13.i15.2263.
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Protein-losing enteropathy and intestinal bleeding. The role of lymphatic-venous connections.蛋白丢失性肠病与肠道出血。淋巴静脉连接的作用。
Ann Intern Med. 1966 Mar;64(3):628-35. doi: 10.7326/0003-4819-64-3-628.
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Am J Dig Dis. 1973 Jan;18(1):54-8. doi: 10.1007/BF01072238.