Almadani Moneer E
Department of Clinical Sciences, Surgery Unit. Almaarefa University Faculty of Medicine, Riyadh, Saudi Arabia.
Turk J Surg. 2025 Sep 3;41(3):219-226. doi: 10.47717/turkjsurg.2025.2025-6-21. Epub 2025 Aug 11.
Obesity is highly prevalent among individuals with cognitive impairments, yet bariatric surgery is often underutilized in this population due to concerns regarding adherence and safety. The aim of this review is to evaluate the outcomes of bariatric surgery in obese adults with cognitive impairments, focusing on weight loss, cognitive function, general health, and postoperative risks. A systematic review of 11 studies was conducted, including case reports, cohort studies, and pilot trials that investigated bariatric surgery outcomes in adults with intellectual disabilities, neurodevelopmental disorders, or acquired cognitive dysfunction. Outcomes included excess weight loss (EWL), cognitive changes, comorbidity resolution, and postoperative complications. Most studies reported significant weight loss, although slightly lower than in neurotypical populations (EWL ranging from 31.1% to 90%). Cognitive improvements were observed in domains such as memory and executive function within weeks after surgery. Bariatric surgery also led to notable improvements in comorbidities such as diabetes and hypertension. However, risks included nutritional deficiencies and poor adherence, particularly in patients with low preoperative cognitive function. Strong caregiver support and structured follow-up programs were key predictors of long-term success. Bariatric surgery can be a safe and effective intervention for adults with cognitive impairments when tailored support systems are implemented. Cognitive screening and personalized postoperative care are essential to optimize outcomes.
肥胖在认知障碍患者中非常普遍,但由于担心依从性和安全性,减肥手术在这一人群中往往未得到充分利用。本综述的目的是评估减肥手术对肥胖且有认知障碍的成年人的疗效,重点关注体重减轻、认知功能、总体健康状况和术后风险。我们对11项研究进行了系统综述,包括病例报告、队列研究和试点试验,这些研究调查了智障、神经发育障碍或后天认知功能障碍的成年人的减肥手术效果。结果包括超重减轻(EWL)、认知变化、合并症缓解和术后并发症。大多数研究报告称体重显著减轻,尽管略低于神经正常人群(EWL范围为31.1%至90%)。术后数周内,在记忆和执行功能等领域观察到认知功能有所改善。减肥手术还使糖尿病和高血压等合并症得到显著改善。然而,风险包括营养缺乏和依从性差,尤其是术前认知功能较低的患者。强大的护理人员支持和结构化的随访计划是长期成功的关键预测因素。当实施量身定制的支持系统时,减肥手术对有认知障碍的成年人可能是一种安全有效的干预措施。认知筛查和个性化的术后护理对于优化治疗效果至关重要。