Gupta Prachi, Sable Nilesh, Prakash Gagan, Menon Santosh
Department of Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Department of Radio-Diagnosis, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Indian J Cancer. 2025 Apr 1;62(2):316-319. doi: 10.4103/ijc.ijc_879_21. Epub 2025 Aug 8.
Primary renal well-differentiated neuroendocrine tumors (WDNETs) are uncommon tumors that differ in histological pattern, biological behavior, and response to treatment. There is a considerable correlation between WDNETs and congenital or acquired renal anomalies. We report a WDNET in a horseshoe kidney with lymph nodal metastasis in a 35-year-old male. This rare occurrence is discussed, especially the grading of these tumors and the value and vagaries of Mib-1 labeling index.
原发性肾高分化神经内分泌肿瘤（WDNETs）是一种罕见肿瘤，在组织学模式、生物学行为及对治疗的反应方面存在差异。WDNETs与先天性或后天性肾异常之间存在显著相关性。我们报告了1例35岁男性马蹄肾伴淋巴结转移的WDNET。本文对这一罕见病例进行了讨论，尤其是这些肿瘤的分级以及Mib-1标记指数的价值和变化情况。
