Deng Yuchun, Liu Meng, Wang Chen, Liu Yurong, Deng Hua, Tang Dongmei, Zeng Linying, Jin Yuping, Cao Donglan, Tao Kaizong, Liu Gang
Zhongjiang County People's Hospital, Zhongjiang County, 96 Dabei Street, Sichuan Province, Sichuan, China.
Sci Rep. 2025 Aug 11;15(1):29327. doi: 10.1038/s41598-025-15648-8.
This study aimed to ascertain the incidence, clinical characteristics, and risk factors of hospital-acquired pressure injuries in neurosurgery inpatients and to provide a reference for preventive care. Adhering to the Strengthening the Reporting of Observational Studies in Epidemiology guidelines, we conducted a prospective cohort study involving 1,192 patients admitted to the Department of Neurosurgery at a grade A tertiary hospital in western China from April 2023 to March 2024. During a total of 14,091 patient-days of follow-up, the incidence density of hospital-acquired pressure injuries was 0.003 per patient-day, with a cumulative incidence of 3.6%. Standardized forms were utilized to collect demographic, clinical, laboratory, and pressure injury data. The study revealed that the buttocks (20 cases, 37%) and sacral region (13 cases, 24.1%) were the predominant sites of hospital-acquired pressure injuries, predominantly presenting as stage 1 (21 cases, 38.9%) and stage 2 (27 cases, 50%) pressure injuries. Edema (P = 0.014) and albumin (P = 0.049) were identified as independent risk factors for the development of hospital-acquired pressure injuries. The results of this study highlight the need to monitor patients' edema status and albumin levels, emphasize the importance of rapid control of acute inflammation, and suggest appropriate albumin supplementation to reduce the risk of hospital-acquired pressure injury.
本研究旨在确定神经外科住院患者医院获得性压力性损伤的发生率、临床特征和危险因素，为预防护理提供参考。我们遵循加强流行病学观察性研究报告指南，对2023年4月至2024年3月在中国西部一家三级甲等医院神经外科收治的1192例患者进行了一项前瞻性队列研究。在总共14091个患者日的随访期间，医院获得性压力性损伤的发病密度为每患者日0.003，累积发病率为3.6%。使用标准化表格收集人口统计学、临床、实验室和压力性损伤数据。研究显示，臀部（20例，37%）和骶尾部（13例，24.1%）是医院获得性压力性损伤的主要部位，主要表现为1期（21例，38.9%）和2期（27例，50%）压力性损伤。水肿（P = 0.014）和白蛋白（P = 0.049）被确定为医院获得性压力性损伤发生的独立危险因素。本研究结果强调了监测患者水肿状态和白蛋白水平的必要性，强调了快速控制急性炎症的重要性，并建议适当补充白蛋白以降低医院获得性压力性损伤的风险。
