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一名接受腋窝淋巴结清扫术患者的胸导管损伤:病例报告

Thoracic Duct Injury in a Patient Undergoing Axillary Lymphadenectomy: A Case Report.

作者信息

Ferreira Michelle Albano, Costa Juliana Oliveira, Araújo Juliana Lopes de Aguiar, de Medeiros Kleyton Santos, Ferreira Larissa Dos Santos Lourenço, de Sousa Ubiratan Wagner, Dantas Macerly Layse de Menezes, Navarro Diana Taissa Sampaio Marinho

机构信息

Department of Mastology, League Against Cancer, Natal, Rio Grande do Norte, Brazil.

Department of Medicine, Potiguar University, Natal, Rio Grande do Norte, Brazil.

出版信息

Case Rep Med. 2025 Aug 4;2025:9720159. doi: 10.1155/carm/9720159. eCollection 2025.

DOI:10.1155/carm/9720159
PMID:40791291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12339139/
Abstract

A 56-year-old female patient, with no significant comorbidities, presented with abnormal breast exam findings. Imaging revealed a 5.4-cm irregular nodule in the left breast, diagnosed as invasive breast carcinoma (NST, Grade 2). Neoadjuvant chemotherapy was initiated, leading to a reduction in lesion size. Surgical intervention included quadrantectomy, sentinel lymph node biopsy, and axillary lymphadenectomy, which revealed residual carcinoma and positive lymph nodes. Postoperatively, chylous drainage through a Portovac drain was observed, prompting reoperation, during which the injured lymphatic duct was identified. Conservative management with medium-chain triglycerides resulted in a progressive reduction of drainage. The patient was discharged on the 13th postoperative day, subsequently underwent adjuvant radiotherapy, and is currently receiving regular outpatient follow-up.

摘要

一名56岁女性患者,无明显合并症,因乳房检查结果异常就诊。影像学检查发现左乳有一个5.4厘米的不规则结节,诊断为浸润性乳腺癌(非特殊类型,2级)。开始新辅助化疗,病变大小缩小。手术干预包括象限切除术、前哨淋巴结活检和腋窝淋巴结清扫术,结果显示有残留癌和阳性淋巴结。术后观察到通过Portovac引流管有乳糜引流,促使再次手术,术中发现淋巴管受损。采用中链甘油三酯的保守治疗使引流逐渐减少。患者术后第13天出院,随后接受辅助放疗,目前正在接受定期门诊随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/6fcae0b2d9f5/CRIM2025-9720159.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/f820cfeac4b5/CRIM2025-9720159.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/ee40d4460f72/CRIM2025-9720159.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/6fcae0b2d9f5/CRIM2025-9720159.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/f820cfeac4b5/CRIM2025-9720159.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/ee40d4460f72/CRIM2025-9720159.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865f/12339139/6fcae0b2d9f5/CRIM2025-9720159.003.jpg

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本文引用的文献

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Anatomic Study of the Integrity of the Breast Lymphatic Network With Indocyanine Green in Breast Implant Surgery Through the Axillary Approach.通过腋窝入路在乳房植入手术中使用吲哚菁绿对乳房淋巴网络完整性的解剖学研究。
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A systematic review of chyle leaks and their management following axillary surgery.
腋窝手术后乳糜漏及其处理的系统评价
Eur J Surg Oncol. 2020 Jun;46(6):931-942. doi: 10.1016/j.ejso.2020.01.029. Epub 2020 Jan 30.
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Evaluating the Use of Octreotide for Acquired Chylothorax in Pediatric Critically Ill Patients Following Cardiac Surgery.评估奥曲肽在小儿心脏手术后重症患者获得性乳糜胸治疗中的应用。
J Pediatr Pharmacol Ther. 2019 Sep-Oct;24(5):406-415. doi: 10.5863/1551-6776-24.5.406.
5
Clinical approach and review of causes of a chylothorax.乳糜胸的临床处理方法及病因分析。
Respir Med. 2019 Oct;157:7-13. doi: 10.1016/j.rmed.2019.08.014. Epub 2019 Aug 22.
6
Chylous Fistula following Axillary Lymphadenectomy: Benefit of Octreotide Treatment.腋窝淋巴结清扫术后乳糜瘘:奥曲肽治疗的益处
Case Rep Surg. 2016;2016:6098019. doi: 10.1155/2016/6098019. Epub 2016 Jan 26.
7
Review of thoracic duct anatomical variations and clinical implications.胸导管解剖变异及其临床意义综述。
Clin Anat. 2014 May;27(4):637-44. doi: 10.1002/ca.22337. Epub 2013 Dec 2.
8
Chylous leakage post mastectomy and axillary clearance: clinical aspect, causes and review of literature.乳房切除术后及腋窝清扫术后的乳糜漏:临床情况、病因及文献综述
Med J Malaysia. 2013 Jun;68(3):262-3.
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[Chylothorax].[乳糜胸]
J Bras Pneumol. 2006;32 Suppl 4:S197-203. doi: 10.1590/s1806-37132006000900006.
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Management of thoracic duct injuries after oesophagectomy.食管癌切除术后胸导管损伤的处理
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