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病例报告:妊娠合并胎盘转移的乳腺癌

Case Report: Breast cancer in pregnancy with placental metastasis.

作者信息

Lin Yongming, Xie Xinru, Wang Jiayi, Chen Hongbing, Wan Ningning, Lin Jianqing

机构信息

Department of Breast Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.

出版信息

Front Oncol. 2025 Jul 28;15:1573915. doi: 10.3389/fonc.2025.1573915. eCollection 2025.

DOI:10.3389/fonc.2025.1573915
PMID:40792282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12336495/
Abstract

With the increasing incidence of breast malignant tumours in the population, some rare cases of breast cancer have been reported. We would like to share with you a case of placental metastasis of a malignant tumour of the breast: the patient was a young woman who was diagnosed with a breast cancer at 31 weeks of gestation. After regular follow-up, a healthy baby girl was delivered by caesarean section at 37 weeks of pregnancy. In a subsequent placenta specimen, the pathologist found distant metastasis of breast cancer to the placenta. This is rare in distant metastases of breast cancer. The patient is currently undergoing further anti-tumour therapy. Through reviewing the relevant literature, we have compiled and discussed the mechanisms related to the possible use of placenta in preventing cancer invasion and how breast cancer in pregnancy can be followed up. We hope that sharing this case will help further clinical and experimental research.

摘要

随着人群中乳腺恶性肿瘤发病率的不断上升,已报道了一些罕见的乳腺癌病例。我们想与您分享一例乳腺恶性肿瘤胎盘转移的病例:患者为一名年轻女性,在妊娠31周时被诊断出患有乳腺癌。经过定期随访,在妊娠37周时通过剖宫产分娩出一名健康女婴。在随后的胎盘标本中,病理学家发现乳腺癌已远处转移至胎盘。这在乳腺癌的远处转移中较为罕见。该患者目前正在接受进一步的抗肿瘤治疗。通过查阅相关文献,我们整理并讨论了胎盘在预防癌症侵袭方面可能的作用机制以及妊娠期乳腺癌的随访方法。我们希望分享这个病例将有助于进一步的临床和实验研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/ab1bcb5058ed/fonc-15-1573915-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/e3c6e6753a0f/fonc-15-1573915-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/5debd38e2703/fonc-15-1573915-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/ab1bcb5058ed/fonc-15-1573915-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/e3c6e6753a0f/fonc-15-1573915-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/5debd38e2703/fonc-15-1573915-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf08/12336495/ab1bcb5058ed/fonc-15-1573915-g003.jpg

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Case Report: Breast cancer in pregnancy with placental metastasis.病例报告:妊娠合并胎盘转移的乳腺癌
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