Zhang Yaqiong, Yang Wenqi, Sun Qi, Han Fangkai, Dong Minjun
Department of Oral and Maxillofacial Radiology, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.
Department of Radiology, School of Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Clin Exp Dent Res. 2025 Aug;11(4):e70191. doi: 10.1002/cre2.70191.
Certain dental diseases in pediatric patients may disturb their sleep, affect their oral health-related quality of life, and result in a negative influence on cognition and behavior. On the other hand, sleep disturbances may also increase the risk or participate in development and progression of dental diseases.
This narrative review aimed to overview of the bidirectional relationship between common dental diseases and sleep disturbances, as well as the potential mechanisms behind.
PubMed, Web of Science, and Google Scholar were searched using the keywords "dental disease," "sleep disturbances," and "children," and only articles published in English were included.
Evidence provided by previous studies has indicated that common dental diseases, including dental caries, temporomandibular disorders, and dentofacial deformities, induced sleep disturbances in children and adolescents. On the other hand, common sleep disturbances such as sleep disordered breathing, obstructive sleep apnea, as well as other sleep problems, including sleep bruxism and sleep profile impairments, have a strong link to oral health conditions in pediatric patients. Alteration of oral microorganism colonization, impairment in the immune system, persistent inflammation, and chronic pain have contributed to sleep disorders triggered by these dental diseases.
Upon identification of dental caries, gingivitis, periodontitis, as well as other dental problems, a checkup on a child's sleep is important, as this may subsequently affect his/her initiation, maintenance, duration, and quality of sleep. Dentists and orthodontists could play a critical role in early detection, prevention, and intervention of the dental health-related sleep disturbances.
儿科患者的某些牙科疾病可能会干扰他们的睡眠，影响其与口腔健康相关的生活质量，并对认知和行为产生负面影响。另一方面，睡眠障碍也可能增加牙科疾病发生的风险或参与其发展和进展过程。
本叙述性综述旨在概述常见牙科疾病与睡眠障碍之间的双向关系及其潜在机制。
使用关键词“牙科疾病”“睡眠障碍”和“儿童”在PubMed、科学网和谷歌学术上进行检索，仅纳入英文发表的文章。
先前研究提供的证据表明，包括龋齿、颞下颌关节紊乱和牙颌面畸形在内的常见牙科疾病会导致儿童和青少年出现睡眠障碍。另一方面，常见的睡眠障碍，如睡眠呼吸紊乱、阻塞性睡眠呼吸暂停以及其他睡眠问题，包括睡眠磨牙症和睡眠状况受损，与儿科患者的口腔健康状况密切相关。口腔微生物定植的改变、免疫系统受损、持续性炎症以及慢性疼痛导致了这些牙科疾病引发的睡眠障碍。
在发现龋齿、牙龈炎、牙周炎以及其他牙科问题后，检查儿童的睡眠情况很重要，因为这可能会随后影响其睡眠的起始、维持、时长和质量。牙医和正畸医生在与牙科健康相关的睡眠障碍的早期发现、预防和干预中可发挥关键作用。
