Simon B R, Wu J S, Carlton M W, Evans J H, Kazarian L E
J Biomech Eng. 1985 Nov;107(4):327-35. doi: 10.1115/1.3138565.
Analytical and finite element models (FEMs) were used to quantify poroelastic material properties for a human intervertebral disk. An axisymmetric FEM based on a poroelastic view of disk constituents was developed for a representative human spinal motion segment (SMS). Creep and steady-state response predicted by FEMs agreed with experimental observations, i.e., long-time creep occurs with flow in the SMS, whereas for rapid steady-state loading an "undrained," nearly incompressible response is evident. A relatively low value was determined for discal permeability. Transient and long-term creep FE analyses included the study of deformation, pore fluid flow, stress, and pore fluid pressure. Relative fluid motion associated with transient creep is related to nuclear nutrition and the overall mechanical response in the normal disk. Degeneration of the disk may be associated with an increase in permeability.
使用分析模型和有限元模型（FEM）来量化人体椎间盘的多孔弹性材料特性。基于椎间盘成分的多孔弹性观点，为一个具有代表性的人体脊柱运动节段（SMS）建立了轴对称有限元模型。有限元模型预测的蠕变和稳态响应与实验观察结果一致，即SMS中长时间蠕变伴随着流体流动发生，而对于快速稳态加载，“不排水”的、近乎不可压缩的响应很明显。确定了椎间盘渗透率的相对较低值。瞬态和长期蠕变有限元分析包括对变形、孔隙流体流动、应力和孔隙流体压力的研究。与瞬态蠕变相关的相对流体运动与正常椎间盘中的髓核营养和整体力学响应有关。椎间盘退变可能与渗透率增加有关。
